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Industry Update: 3 Exciting Precision Oncology Players to Watch Following Summit’s Meteoric Rise: Silexion, Nuvectis, Scorpian

Global Markets News

Summit Therapeutics (NASDAQ: SMMT) recently captured headlines with the release of its Phase 3 data for ivonescimab, a targeted NSCLC therapy that has generated substantial buzz. The results from its trial conducted in China showed a dramatic 49% reduction in the risk of disease progression or death compared to Merck’s Keytruda, signaling a potentially disruptive force in NSCLC treatment. However, the news wasn’t without its concerns—since the trial data originates from China, there are questions about its applicability to broader, global populations. As noted by BMO Capital Markets’ Evan Seigerman: “Results may or may not be generalizable beyond the China-focused patient population initially assessed.” Despite this, Summit’s valuation has risen by over 100%, now approximating $19 billion. With such a high valuation, the company could see limited room for further significant gains, leading many in the industry to explore other emerging opportunities in precision oncology. Alongside Summit, there are quite a few other players in the field. Some if these companies have even already shown promising initial results and could see similar success in the future if they were to report positive results. These emerging players are worth watching for those interested in following precision oncology drug candidates and pipelines. Among them are precision oncology innovators such as Silexion Therapeutics, Nuvectis Pharma, and Scorpion Therapeutics, which we discuss below. Silexion Therapeutics: Disrupting the KRAS-Driven Cancer Space Silexion Therapeutics (NASDAQ: SLXN) is another under-the-radar player in the precision oncology space, with a focus on KRAS-driven cancers—a notoriously difficult target in oncology. While current small-molecule KRAS inhibitors are making progress, they are often limited to specific mutations, such as KRAS G12C, which accounts for a small percentage of cancers. Silexion’s RNA interference (RNAi) approach offers a broader solution, targeting a wider spectrum of KRAS mutations, particularly in pancreatic cancer, one of the deadliest and most treatment-resistant cancers. At the heart of Silexion’s approach is its LODER™ platform, which delivers siRNA directly to the tumor site, silencing KRAS mutations at the genetic level. This localized delivery not only increases efficacy by concentrating the treatment in the tumor, but it also reduces systemic side effects. Silexion’s next-generation candidate, SIL-204, is an optimized siRNA formulation designed to target pan-KRAS G12x mutations, positioning it to treat a broader range of KRAS-driven cancers beyond pancreatic cancer, such as lung and colorectal cancers. In Phase 2 trials for locally advanced pancreatic cancer, Silexion's LODER™ platform showed a 9.3-month improvement in overall survival when combined with standard chemotherapy. Additionally, the objective response rate (ORR) increased from 20% with chemotherapy alone to 55% with the combination, and in some cases, tumors that were initially non-resectable became operable after treatment with LODER™. These results are especially encouraging given the limited options available for pancreatic cancer patients. SIL-204, is expected to enter Phase 2/3 clinical trials in 2025-2026. What makes Silexion particularly intriguing is its current market valuation. Valued at aproximatly just ~$9 million following its SPAC merger, the company’s valuation could be perceived as low when compared to some of its peers, especially given its innovative technology and promising clinical achievements. Some have wondered whether this low valuation has more to do with dynamics post-SPAC companies. If Silexion can report positive results in its later-stage trials, the company’s outlook could dramatically improve, reflecting the potential of its RNAi-based platform. Like NXP900, SIL-204 could potentially have vast applications across multiple KRAS-driven cancer types, making Silexion a company to watch closely as it advances through clinical development. Nuvectis Pharma: Targeting NSCLC and Beyond by Inhibiting SRC/YES1 Kinases Nuvectis Pharma (NASDAQ: NVCT) has been quietly making strides in the precision oncology sector, developing innovative therapies aimed at overcoming treatment resistance in hard-to-treat cancers. Its lead candidate, NXP900, targets NSCLC by inhibiting the SRC/YES1 kinases, which play critical roles in cancer cell survival and resistance to current therapies. This approach positions NXP900 as a potential game-changer in the treatment of NSCLC, particularly in patients who have developed resistance to EGFR and ALK inhibitors, such as AstraZeneca’s Tagrisso and Novartis’ Alecensa. NXP900 is still in the early stages of clinical development, currently undergoing Phase 1 trials. However, preclinical studies have already shown that it has strong anti-tumor activity in resistant NSCLC models. Even more promising is its potential application beyond NSCLC. Like Summit's ivonescimab, NXP900 focuses on resistance, but it also has broader applications due to its ability to target multiple cancer types driven by SRC/YES1 pathways. This versatility makes it a promising asset not just for NSCLC but also for other difficult-to-treat cancers like squamous cell carcinomas. In addition to NXP900, Nuvectis is advancing NXP800, another precision oncology candidate that is further along in the clinical development process. NXP800 is currently in Phase 1b trials, targeting ARID1a-mutated cancers such as ovarian and endometrial cancers. The early clinical data for NXP800 is promising, showing positive responses in patients with platinum-resistant ovarian cancer. With two strong candidates in the pipeline, Nuvectis is positioning itself as a formidable player in the precision oncology landscape. As Summit’s ivonescimab continues to gain attention, Nuvectis’ earlier-stage NXP900, with its NSCLC focus and beyond, could see similar success in the future if clinical results continue to trend positively. Scorpion Therapeutics: Pioneering Mutant-Selective Therapies Scorpion Therapeutics is redefining the frontier of precision oncology with its focus on delivering highly selective small molecules targeting validated and previously undruggable cancer mutations. Its lead candidate, STX-478, is a mutant-selective, allosteric PI3Kα inhibitor currently in Phase 1/2 trials for advanced solid tumors. Early data presented at the ESMO Congress 2024 highlighted its potential, with STX-478 demonstrating a 23% overall response rate in breast cancer and a 21% response rate across all tumor types, positioning it as a potentially best-in-class PI3Kα inhibitor. STX-478 is notable for its ability to spare wild-type PI3Kα activity in normal tissues, avoiding the toxicities seen with previous PI3Kα inhibitors, such as hyperglycemia and rash. Tumor reductions were seen in 72% of patients treated with STX-478 as a monotherapy, with circulating tumor DNA levels dropping in 86% of patients. This mutant-selective precision could help overcome the limitations of existing PI3Kα inhibitors, which have struggled with dose-limiting toxicities. In July 2024, Scorpion raised $150 million in a Series C financing round, co-led by Frazier Life Sciences and Lightspeed Venture Partners. The additional funding will support the advancement of STX-478 and other pipeline assets, positioning Scorpion for further clinical success. Scorpion’s pipeline includes a broad range of wholly-owned compounds that target both validated and novel cancer targets, positioning the company for future expansion into larger patient populations. As STX-478 progresses through clinical development, Scorpion is poised to become a significant player in the precision oncology space, making it another company worth watching closely. Optimistic Outlook for Precision Oncology The precision oncology space is experiencing a golden era of innovation, with companies like Summit Therapeutics, Nuvectis Pharma, Silexion Therapeutics, and Scorpion Therapeutics leading the charge. As the focus shifts towards targeted therapies that address resistance mechanisms, the market is increasingly favoring companies with novel approaches and broad applications. Summit’s meteoric rise has shown that there is tremendous potential for companies that can demonstrate efficacy in overcoming cancer resistance. While Summit has already captured much of the current attention, companies like Nuvectis, Silexion, and Scorpion, with their earlier-stage pipelines, offer exciting opportunities for the industry to keep a close eye on. As these companies continue to report clinical data and advance through trials, the potential for breakthroughs in treating some of the most difficult cancers grows stronger. With targeted therapies offering the possibility of overcoming resistance without the need for chemotherapy, the future of cancer treatment looks brighter than ever. For those in the oncology space, keeping a close eye on emerging players like Nuvectis, Silexion, and Scorpion could lead to transformative developments as the field of precision oncology continues to evolve. * * * This update may include speculative forward looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those in the forward-looking statements as a result of various factors. the BioTech and Pharma industries are volatile and risky and readers are advised to seek out preffesional advice in the relevent feilds from licensed profesionals. This update is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. [ https://justpaste.it/ch2qt/pdf ]. Global Markets News Network is a commercial digital brand compensated to provide coverage of news and developments related to innovative companies as detailed in the full documentation and it is thus subject to conflicts of interest. Contact Details News Coverage ronald@futuremarketsresearch.com

September 19, 2024 07:45 AM Eastern Daylight Time

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HTX DAO x TRON TOKEN2049 Afterparty: Leading the Next Decade of Web3 Ecosystem

HTX

September 18, Singapore - Today, HTX DAO and TRON, in collaboration with Alethea AI, Tour Billion, BitWave, ChainGPT, Google Cloud, and The Block, hosted an afterparty following TOKEN2049, one of the world’s most influential Web3 events. This highly anticipated crypto night brought together over 1,100 Web3 pioneers to discuss the future of the Web3 ecosystem, with TRON founder and Global Advisor of HTX, Justin Sun, and several industry leaders delivering addresses. The afterparty attracted prominent projects, investment institutions, and KOLs from the crypto space. Notable media partners were in attendance to cover the event, including Odaily, BlockBeats, Foresight News, TechFlow, MarsBit, Cointime, DeThings, PANews, Jinse Finance, ChainCatcher, MetaEra, BroadChain, Bitcoin.com, BeInCrypto, Blockopedia, and Monsterblockhk. As the keynote speaker, Justin Sun highlighted the achievements of HTX and TRON while outlining a twin-engine strategy for future development in his video address titled "A New Decade: TRON x HTX Lead the Globe Web3 Ecosystem." He emphasized that blockchain technology, once a nascent concept, has now become a transformative force in reshaping industries worldwide and lauded TRON and HTX for playing pivotal roles in this evolution. "TRON's journey began with an attempt at an in-depth exploration of the limitless possibilities of blockchain technology. We remained committed to the core values of openness, transparency, and decentralization. Furthermore, HTX, one of the most important partners of TRON, has made remarkable contributions to the growth of the blockchain industry since its inception. This year marked the 11th anniversary of HTX, showing its longevity in this industry, and that is truly an achievement to be proud of. HTX has remained at the forefront of the industry, owing to its commitment to longtermism, proactive compliance to changing regulations, and its unwavering focus on security and user experience,” Sun added. Looking ahead to Web3's next decade, Sun believes blockchain technology and products need to focus on real-world applications, which requires enhanced interactivity, diversified use cases, AI-driven solutions, strengthened network systems, and broader acceptance. The upcoming decade will also witness closer collaborations between TRON and HTX. The most recent collaboration between the two industry giants took place in August with SunPump. This meme coin issuance platform, launched on the robust TRON network and supported by HTX’s market resources, became a phenomenal Web3 application in just one month of its debut. SunPump boosted on-chain transaction volume, creating a positive feedback loop that benefitted both TRON and HTX. "Our ultimate goal is to build an all-encompassing Web3 ecosystem that integrates payments, investments, and social interactions," said Justin Sun. "We will focus on driving the growth of the TRON ecosystem, drawing in more high-quality DApps and projects and enhancing the collaboration between TRON and HTX. Meanwhile, we will also tap into HTX's global influence and extensive resources. By integrating TRON’s cutting-edge technology with HTX's market strength, we can expand the global reach of our products and services with greater efficiency." In addition to Justin Sun, the event is also attended by several distinguished guests from prominent projects and media, including Arif Khan, founder and CEO of Alethea AI, an AI infrastructure provider; Victor Yap, Regional Marketing Director for Asia Pacific at Tour Billion, a GameFi launchpad; Leo, co-founder of BitWave, a Bitcoin layer-2 solution; Sharon Sciammas, CMO of ChainGPT, an AI tool provider; and Larry Cermak, CEO of The Block, a crypto media outlet. They each delivered speeches, sharing their insights and future perspectives on the crypto industry. Their discussions covered a range of trending topics, such as, AI, DePIN, BTCFi, and GameFi. It is worth mentioning that the event also captivated attendees with energetic performances and a variety of thrilling prize draws. The evening’s lucky winners took home a range of remarkable rewards, such as, 11 cold wallets, 2.2 billion $HTX, 5 $ETH, $2,000 in $MASA, and 2 Formula 1 tickets. At TOKEN2049 in 2023, HTX marked its 10th anniversary with a rebranding, representing the first milestone in its journey into the next decade. Over the last year, HTX has achieved substantial growth, consistently leading the industry in terms of trading volume and liquidity, while regularly introducing innovative products and high-quality assets. According to CoinGecko data, HTX became the second-ranked exchange globally in early August, making steady progress toward its goal of securing a spot in the top three exchanges. Furthermore, the establishment of HTX DAO represents another milestone in HTX's efforts to build a decentralized ecosystem. To date, with the support of HTX, the liquidity pledges received by HTX DAO and the amount of $HTX repurchased and burned have reached a total of $51.5 million, effectively driving the growth of the decentralized community. This year, participants from the HTX ecosystem remain active at TOKEN2049. In addition to the Afterparty hosted by TRON and co-hosted by HTX DAO, Edward, the Managing Partner of HTX Ventures, HTX’s global investment arm, will participate in a discussion hosted by Google Cloud on the theme “AI and Web3: Building a Trusted Digital Future.” HTX's global brand building has achieved initial success and is set to expand further. As a pioneer in the crypto space, HTX has consistently spearheaded industry innovation and led the way in setting new trends over its 11-year history. Looking forward, HTX will continue to pursue its vision of achieving financial freedom for 8 billion people on earth. As Justin Sun stated, “With the joint efforts of HTX and TRON, we are confident that we can create a truly practical, convenient, and thriving Web3 ecosystem for users worldwide within the next decade.” About HTX Founded in 2013, HTX has evolved from a virtual asset exchange into a comprehensive ecosystem of blockchain businesses that span digital asset trading, financial derivatives, research, investments, incubation, and other businesses. As a world-leading gateway to Web3, HTX harbors global capabilities that enable it to provide users with safe and reliable services. Adhering to the growth strategy of "Global Expansion, Thriving Ecosystem, Wealth Effect, Security & Compliance," HTX is dedicated to providing quality services and values to virtual asset enthusiasts worldwide. Contact Details Ruder Finn Asia htx@ruderfinn.com Company Website https://www.htx.com About HTX Founded in 2013, HTX has evolved over a decade from a simple cryptocurrency exchange to a comprehensive blockchain business ecosystem. This expansion covers a wide range of services including digital asset trading, financial derivatives, wallets, research, investments, incubation, and more. As a world-leading portal to Web 3.0, HTX is committed to a growth strategy focused on global expansion, ecological prosperity, wealth effect, and safety and compliance. This approach enables us to offer comprehensive, safe, and reliable services and value to virtual currency enthusiasts around the world, reinforcing our position as a global gateway to Web3. Contact Details Ruder Finn Asia htx@ruderfinn.com Company Website https://www.htx.com/

September 18, 2024 11:19 PM Eastern Daylight Time

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Reform of Africa's Criminal Justice Systems

Pinion Newswire

A well-functioning criminal justice system (CJS) is the bedrock of a safe and secure society. It protects our communities from exploitation and our citizens against false accusations. The CJS comprises government agencies mandated through legislation to work together to deter crimes against individuals, societies, and states. In a collaborated effort, they serve to punish offenders who cause physical or psychological harm against persons, are involved in damage or theft of property, and those who perform crimes against the state. Criminal justice systems involve multiple parts, each with a distinct role. The adversarial nature of most criminal justice systems requires functional independence between the judiciary and the agencies that present criminal cases to courts on behalf of the people. Criminal justice systems are inherently complex because of the independent functioning of agencies such as police investigation, prosecution, judiciaries, and prison authorities. They involve several independent functions: crime reporting, detection, prosecution, adjudication, sentencing, incarceration, rehabilitation, and reintroducing prisoners into society. While there is a requirement for independence, each component depends on one or more of the other components, without which it cannot function. Social Deprivation A large percentage of crimes in Africa can be directly attributed to social deprivation caused by poor housing and parenting, poverty, low levels of education, and unemployment. Socially deprived individuals are easily given over to more detestable behavior, such as substance abuse and gangsterism, where there is no respect for human life and freedom and no regard for the rule of law. African countries have also become havens for crimes such as fraud, corruption, extortion, kidnapping, human trafficking, and modern slavery. Unlike the modus of operandi in the age of colonial slavery, greedy people from within African countries who operate in concert with international syndicates have become the main actors. Criminal Justice Realities CJS agencies worldwide are poorly coordinated and function in silos. Petty crime cases take as long to finalize as complex cases because of a lack of case classification and appropriate diversion programs. Very few, if any, countries can claim that they have successfully integrated their criminal justice process and information flows. Blame will frequently be shifted to different areas of the system, with budget limitations often cited as the primary obstacle. However, most criminal justice systems are fraught with inefficiencies that lead to wastage and duplication, leading to a continuous cycle of increasing inefficiencies. Criminal justice systems almost everywhere in Africa suffer from a lack of end-to-end governance and the absence of politically accountable individuals who can influence strategic government expenditure and oversee the alignment and smooth functioning of the system as an integrated whole. Some African countries have taken promising steps toward integrating their criminal justice systems and have sound process and information integration plans. This has, however, been hampered by a lack of continuity of decision-makers and functional heads across CJS agencies. Changes at the ministerial level frequently trigger shifts in leadership across subordinate appointments, which in turn result in strategic and operational pauses for long periods and disruption of previous integrated planning and systems implementation. Appropriate Tools Budgets are mostly allocated to the different CJS components in an unscientific and uncoordinated way, creating unbalanced systems that result in blockages from start to finish. The process is characterized by multiple iterations between investigators and prosecutors and many fruitless court appearances that result in postponements before court adjudication. The result is a very high rate of cases that are closed by the police as “undetected” and an alarmingly low conviction rate. This translates into a criminal justice system that does not serve as a deterrent to crime. A cursory survey among crime detectives in Africa will almost always point to lacking basic but essential tools, such as vehicles to transport them to crime scenes, limiting available access to witnesses, prosecutors, and attending court hearings. They often must share mobile phones, which serve a dual purpose as recording and photographic devices. Forensic investigators face similar issues. Prison Overcrowding Most African prisons are overcrowded. The number of convicted prisoners almost always exceeds prison capacity. Prisons also have to accommodate high numbers of offenders who are awaiting trial. They should be kept separately from sentenced prisoners, but this is not always the case. The result is that young first-time offenders are often locked up in the same ultra-crowded spaces as individuals with extensive criminal records. Recommendations for Criminal Justice Reform The success of criminal justice systems depends on their ability to function seamlessly, with balanced and optimized resource utilization across the CJS entities and performance measured on an end-to-end basis. Successful CJS reform interventions have political and executive backing at the highest levels, ensuring they maintain a sustained involvement in the ongoing performance of the CJS. The critical factors are listed below: Focused and integrated governance and oversight structures backed by senior political sponsors and high-level officials. A single vision, mission, and overall CJS objectives at federal, provincial/state levels. Coordinated strategies, plans, and budgets, including cross-departmental resource models. A legislative reform program to replace inhibiting and outdated legislation, to enact legislation, and to publish diversion programs and alternative dispute resolution regulations, thereby allowing CJS role players to focus on serious crimes. Implementation of a permanent CJS structure to: Specialist career paths for investigators, prosecutors, and judiciary members who deal with complex commercial crime cases and other emerging crimes, including cybercrimes. Integrated and accessible CJS information technology system with shared criminal case information, criminal history, and biometric information of sentenced offenders. Outcomes The recommended actions will have strategic and operational benefits for society and criminal justice actors, with tangible and measurable outcomes that include: Successful investigations with fewer iterations between prosecution and investigation. Reduced number of court postponements, offender remands, and a decreased “awaiting trial” population. Shorter criminal case lapse time and increased cases with a final verdict. Significant elimination of duplication and wastage of public funds. Improved public confidence. Conclusion Effective criminal justice can only be served when all the role players are aligned through a joint mandate, common overall objectives, and coordinated and managed operating processes and procedures. This is contrasted by disjointed criminal justice systems that work in silos. This truth has evaded the attention of politicians, government agency heads, and CJS strategists for many decades. Insufficient attention to joint capacity planning, headcount balancing, skills requirements, skills matching, legislative alignment, and reform initiatives, results in delayed justice or no justice. A well-thought-through strategic approach to problem identification and solving, combined with the active involvement of the highest level of decision-makers, will result in actions that will automatically allow for short-term quick fixes, medium-term solutions, and longer-term interventions that ultimately must all be incorporated into a strategic Criminal Justice Reform Program. Contact Details StudeBaker Group Johann Marx +1 917-601-3863 johann@studebaker.group

September 18, 2024 04:41 PM Eastern Daylight Time

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Bluepeak Reaches Major Milestone of 100,000 Customers

Bluepeak

Bluepeak, a leading provider of high-speed fiber internet, has reached a significant milestone, surpassing 100,000 subscribers across the states of South Dakota, southwest Minnesota, Oklahoma, Wyoming and North Dakota. Bluepeak is dedicated to providing more high-speed, fiber internet choices to underserved areas, driven by principles of transparent pricing, honest communication, and local customer support. Since rebranding as Bluepeak in 2022, the company has rapidly expanded across the region, bringing high-speed fiber internet to areas that have long been overlooked. As part of its expansion efforts, early markets were chosen for their vibrant communities, strong partnerships, and a clear need for improved internet services. More than just numbers, this connectivity is creating new opportunities in education, healthcare, and business for residents. “We are incredibly proud to have reached this milestone. It reflects not just our growth, but the trust and support of our valued customers,” said Rich Fish, Bluepeak CEO. “This achievement underscores our commitment in providing a better choice in areas that have gone underserved for far too long. As we continue to expand and bring fiber to new markets, we remain steadfast in our mission to deliver exceptional services and enhanced connectivity.” Bluepeak’s dedication to delivering fast, reliable, and affordable fiber internet remains unwavering. Over the next year, the company plans to extend its reach to new communities, continuing to invest in market expansions with exciting announcements on the horizon, including new efforts in Texas. Residents across the Great Plains and Midwest interested in Bluepeak services can check for availability at mybluepeak.com. About Bluepeak Bluepeak is a new kind of internet provider bringing fast, reliable, affordable internet to places that have needed better options for too long. The company has roots serving Great Plains and Midwest communities going back more than 30 years. As the need for internet in the region has evolved, so has Bluepeak, upgrading and expanding service in South Dakota, southwest Minnesota, Oklahoma, Wyoming, North Dakota, and soon-to-be Texas, with the newest cutting-edge technology. These expansion efforts include multi-million-dollar infrastructure projects, community involvement and growth through local hires. Bluepeak is earning the trust of customers and businesses through simple, affordable offerings, responsive, reliable customer service and transparent pricing. The company’s unique approach to delivering internet service has earned Bluepeak accolades for customer satisfaction, network performance, workplace culture and meaningful community partnerships. Visit www.mybluepeak.com to learn more. Contact Details Parnomi PR, on behalf of Bluepeak Angie Knight +1 574-208-9090 media@parnomi.com Company Website https://www.mybluepeak.com

September 18, 2024 09:00 AM Mountain Daylight Time

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Green Global FX Introduces AI-Powered Signals App for Australian Investors

Rev Up Marketers

Green Global FX, located at Ms Marie Murray, 75 Hayes Hill, Bromley, England, BR2 7HN, has unveiled its new AI-powered signals app, designed to provide real-time data and insights for stock investments. This innovative app aims to transform the way Australian investors engage with stock market opportunities by offering cutting-edge tools that enable informed, data-backed decisions. As the financial markets continue to shift, Australian investors are increasingly seeking tools that deliver both precision and speed. The Green Global FX signals app leverages artificial intelligence to analyze market data in real time, allowing users to access stock signals that help them capitalize on market opportunities with greater efficiency. AI-Powered Signals: Revolutionizing Stock Market Insights Powered by advanced AI technology, the Green Global FX app processes vast amounts of market data instantly. Traditional stock analysis often requires time-consuming manual effort, but the Green Global FX app delivers actionable signals directly to users' devices, enabling them to make rapid, well-informed decisions. "Our goal with this app is to provide Australian investors with the tools they need to stay ahead of market trends," said James Smith, CEO of Green Global FX. "In today’s fast-moving financial landscape, having access to real-time insights is crucial for making swift, effective investment decisions." How the Signals App Benefits Australian Investors One of the app's key advantages is its ability to provide stock signals without the need for constant market monitoring. Investors receive notifications when opportunities arise, allowing them to act quickly based on AI-generated insights. This feature ensures that Australian investors remain connected with the latest market trends, ultimately enhancing their decision-making capabilities. Personalized Stock Signals Tailored to Investors' Needs The Green Global FX app also offers personalized stock signals, tailored to individual preferences such as risk tolerance, investment goals, and preferred stocks. This customization allows investors to act on opportunities that align with their specific strategies, making stock market investing more targeted and effective. The Future of Stock Investing with AI As AI technology continues to influence the financial sector, tools like the Green Global FX signals app are becoming essential for investors aiming to stay ahead of the curve. By providing accurate, real-time insights, Green Global FX empowers users to make smart investment decisions based on the latest market movements. "Our AI-powered app is designed to give Australian investors an edge in stock investing," said James Smith. "We’ve received overwhelmingly positive feedback, and we look forward to continuing to help investors succeed." About Green Global FX At Green Global FX, we believe that understanding the stock market should be accessible to everyone. That’s why we developed a free, easy-to-use signals app designed to give users an edge in their trading decisions. Our app provides real-time market indicators, helping both beginners and experienced traders make informed choices. Whether you're looking to analyze stock trends or gain deeper insights into market movements, our tool is here to support you. Our goal extends beyond just offering a tool; we aim to build a thriving community of traders who can learn, grow, and succeed together. We encourage collaboration, shared experiences, and a deeper understanding of the stock market to create an inclusive environment for continuous learning and improvement. For more information, visit Green Global FX. Disclaimer The information provided by the Green Global FX app is for educational and informational purposes only and should not be considered financial advice. Investment in stocks and other financial instruments carries risk, and individuals should conduct their own research or consult with a financial advisor before making any investment decisions. Contact Details HAYES HILL ROAD FUND LIMITED James Smith jamess@greenhillfund.net Company Website https://www.greenhillfund.net/

September 18, 2024 10:26 AM Eastern Daylight Time

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MANDUKA® Launches the Dhara Yoga Apparel Collection for Women

Manduka

Manduka, creators of high performance yoga gear and the #1 choice of yoga teachers worldwide, revealed today its Dhara collection, a five-piece line of foundational yoga apparel designed for comfort, movement, and sustainability. Honoring a request from the yoga community to provide apparel they can feel good about wearing and how it is made, the Dhara collection was created with the highest standards in performance and sustainability. It’s the newest drop in the company’s plan to set the benchmark for environmentally conscious leadership in the performance wellness industry through 2025. The Dhara Collection offers a simple and easy to wear combination of premium quality, sustainability, and performance in yoga apparel. It’s designed with 88% recycled materials, a difference you can actually feel when wearing. The collection is also free from many of the harmful chemicals that can be found in other performance wear like pesticides, BPA, PFAS and formaldehyde. Technical, breathable and buttery soft, it addresses the demand for thoughtfully designed activewear that doesn’t compromise on style or functionality. “Manduka is on a path to elevate the performance and sustainability of its hardgoods and apparel lines over the next several years,” said Pamela Levine, CEO Manduka. “You will see Manduka build on its legacy of creating soulfully engineered products through usage of renewed materials, innovative manufacturing methods, and pre and post consumer waste reduction efforts. We are excited to unveil the Dhara collection as the first in this roadmap to further seamlessly integrate Manduka’s high-performance standards with a deep commitment to sustainability at a level not yet seen in the industry.” The translation of Dhara means earth with an homage to create a product with attention to the recycled materials that make up this collection. The timeless pieces are designed to offer a second skin feel that enhances your practice and doesn’t distract. The Dhara collection is made up of five ultra-soft pieces including: Dhara Bra - sleek, supportive pullover bra with four-way stretch. Features a flattering scoop neckline, low open back, and hidden underbust band. Dhara Capri Legging - high waisted fit and sleek styling makes it a versatile cropped legging with long lasting comfort. Dhara Tank - sophisticated racer back tank with a modest cropped fit. Designed with a double-knit construction with four-way stretch allows you to flow effortlessly. Dhara Legging - high waisted fit and sleek styling makes it a versatile legging with long lasting comfort. Created with a matte finish fabrication and four-way stretch ensure you move effortlessly and feel at one with your body. The Dhara collection is available in a range of colors like Avian Heather, Clay Heather, Midnight Heather, Phantom and Lions Mane and has an MSRP of $58-$90. The line will be available through www.manduka.com yoga studios and select national retailers. About Manduka Manduka was founded in 1997 with the simple idea that a better yoga mat could make a world of difference. For generations, Manduka has revolutionized the yoga space by providing purposefully crafted products that enable a more joyful practice, whatever that looks like for you. The brand's name pays homage to the Mandukasana, a challenging, thought-provoking, and freeing pose that inspires joy, laughter, and simplicity. Their loyal community of teachers, yogis and enthusiasts have been cultivated by the quality, intentionality, durability, and performance of their Mats and yoga accessories. Their unparalleled craftsmanship and sustainability efforts remain celebrated widely in wellness communities throughout the world. From their teacher-recommended PRO Series Mat to their Free Online Yoga Classes, Manduka is on a mission to inspire daily practice in all its modern forms for those seeking connection to self and humbly works in service of the community. Practice On. Website | Instagram | TikTok | YouTube Contact Details Amber Cardullo amber@harmonica.co Company Website https://www.manduka.com

September 18, 2024 09:21 AM Eastern Daylight Time

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Trade Warehouse Launches New Range of Guttering Materials for UK-Based Construction Companies

Rev Up Marketers

Trade Warehouse, a leading supplier of construction materials, has launched a new range of guttering materials designed to meet the needs of UK-based construction companies. The collection includes cast iron, aluminum, and steel guttering systems, all engineered to endure the UK's harsh climate while offering aesthetic appeal. This range is particularly beneficial for companies working on traditional and heritage buildings, as the cast iron gutters combine durability with a classic design. The cast iron systems are rust-resistant and designed to preserve the architectural integrity of period properties while offering modern functionality. This product line caters to builders seeking reliable and visually consistent materials for restoration projects. In addition to cast iron, the company’s aluminium guttering products provide an eco-friendly option. Fully recyclable and lightweight, these materials are ideal for builders focused on sustainable construction practices. The aluminium gutters are corrosion-resistant, reducing maintenance needs while offering long-term environmental benefits. Trade Warehouse is dedicated to supporting construction professionals with top-notch customer service. They offer free samples of their guttering materials, allowing construction companies to evaluate the quality before making significant purchases. Their expert advice on installation and maintenance further enhances customer experience, ensuring builders can confidently choose the best materials for their projects. Trade Warehouse has been a trusted supplier for the UK construction industry, known for its high-quality products and exceptional service. The company’s dedication to providing reliable, cost-effective, and sustainable solutions continues with this latest collection, designed to help construction companies meet the demands of modern and traditional building projects alike. For more information about Trade Warehouse’s new guttering range, visit www.tradewarehouse.co.uk or contact their customer service team at info@tradewarehouse.co.uk. Contact Details Trade Warehouse Elliot McHugh info@tradewarehouse.co.uk Company Website https://tradewarehouse.co.uk

September 18, 2024 09:17 AM Eastern Daylight Time

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BEVEL, THE AWARD-WINNING MEN’S GROOMING BRAND SUPPORTS INVEST FEST ENTREPRENEURS WITH $25,000 GRANT

Bevel

Atlanta-based, leading men’s head-to-toe grooming brand Bevel, is proud to present a $25,000 business grant to marketplace vendor Double Dutch Aerobics. Invest Fest is a first of its kind, in-person experience that combines investing, entrepreneurship, pop culture, and entertainment in a festival setting. The festival is where commerce and culture meet at a unique intersection for the empowerment of our community. Bevel is proud to support the community and this innovative fitness program. As the official grooming partner of the 4th annual Invest Fest, Bevel, selected the pioneering fitness business Double Dutch Aerobics, founded by Double Dutch World Champion Michelle Clark and Sean Clark, Master Double Dutch Aerobics Instructor, from over 300+ conference vendors. Double Dutch Aerobics, is also based in Atlanta, Georgia. Founded in 2013 by Tristan Walker, an entrepreneur who identified a need in shaving products and tools for himself and other men like him, Bevel was born from Black entrepreneurship and ingenuity. A decade later, Bevel has revolutionized grooming industry standards and offers a range of premium hair, beard, shave, skin, and body care products that prioritize the needs of Black and brown men. Furthermore, the Atlanta-based brand remains committed to looking for opportunities to best serve its customer and its community. Bevel CEO, Damon Frost, announced the grant donation on the Monday, September 9 th, 2024 episode of Earn Your Leisure’s Market Mondays Podcast. Under the Earn Your Leisure Network, Invest Fest is a premier event focused on financial empowerment and entrepreneurialism. Held on August 23 rd – 25 th 2024 in the Georgia World Conference Centre, the conference included presentations, panels and workshops on investing, entrepreneurship, pop culture and entertainment. The festival-style event enables attendees to network with industry trailblazers, connect with other business owners and even pitch their business ideas for grants. Headquartered in Atlanta, Bevel’s partnership with Invest Fest is a continuation of the brand’s track record of serving its customer and its community through giveback initiatives. The 3-day conference equips many in the community with tools to grow and expand their financial wellness and entrepreneurial ventures. “At Bevel, we are committed to serving our customers with product solutions to address their unique grooming needs and through giveback initiatives that we believe make a real impact in the community,” said Bevel Marketing Leader Breann Davis. “We are grateful to Rashad, Troy and the entire Invest Team for allowing us to partner with amazing companies like Double Dutch Aerobics and elevate the next generation of entrepreneurs who share our commitment to the community.” Bevel products, razors and trimmers are available on www.getbevel.com, Amazon.com, Ulta.com and ULTA Beauty stores, Target.com and Target stores, Walmart.com and select Walmart stores. About Walker & Company Brands Walker & Company Brands, recently acquired by Procter & Gamble, is a family of brands designing health and beauty solutions for people of color. Our vision is to build the world's most consumer-centric health and beauty products company, inspiring unprecedented customer loyalty. With the introduction of the first brand Bevel, Walker & Company launched in 2013. Bevel provides grooming products for Black men, including a full Skin Care regimen, a Shave System, and the Bevel Trimmer, and services designed to help reduce skin irritation and razor bumps. To learn more about Walker & Company Brands, visit www.walkerandcompany.com. About Overtime Elite Overtime Elite is an eight-team league with teams based in Atlanta and other cities around the country. The teams feature some of the top 17-19 year old basketball players globally, both professional and amateur. OTE, owned and operated by Overtime, brings fans as close as possible to the action through broad digital distribution on social accounts with nearly 100 million followers and a streaming deal on Amazon Prime Video. OTE provides two paths - a professional, salaried path and a scholarship path for amateurs, and every player gets the same access to world-class coaching, state-of-the-art training facilities and integrated data and analytics, in addition to a rigorous and customized academic program at OTE Academy. OTE is sponsored by adidas, Bevel, Gatorade, GMC, State Farm and Topps. Contact Details First and Last PR +1 201-569-2080 Bevel@firstandlastpr.com Company Website https://getbevel.com

September 18, 2024 09:10 AM Eastern Daylight Time

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Why Nvidia, Daimler Truck, Nikon And Top U.S. Security Organization Are Partnering With This AI Chip Stock

Benzinga

By Meg Flippin, Benzinga A boom in automated passenger cars and trucks could be coming to roads and highways near you thanks to the companies churning out the technology required to make this a reality. One company, in particular, is Aeva Technologies Inc. (NYSE: AEVA), which makes LiDAR sensors for self-driving vehicles, trucks, trains and more. The sensors act as eyes, providing 3D views of the surroundings with a twist – adding a fourth measurement dimension of speed in what the company calls 4D LiDAR. The company’s sensors are powered by its Frequency Modulated Continuous Wave (FMCW) 4D LiDAR technology, which uses a low-power continuous laser beam to measure distance and velocity for each pixel at the same time. Aeva says FMCW unlocks new levels of safety and automation by instantaneously discriminating between moving and non-moving points and identifying the precise velocity of objects in motion. Per pixel instant velocity data gives real-time insights into how an object’s speed and position change and the direction that change happens with centimeters per second precision, giving the vehicle’s computer a more accurate picture and a faster look-ahead to help plan its next move more quickly. The company says its FMCW LiDAR sensors can also enable self-driving cars and trucks to achieve highway speeds (65 MPH and above) safely. It’s something that the industry has struggled with, with many advanced assisted driving and traffic-jam pilot self-driving vehicles achieving top speeds of only up to 45 MPH. For the automotive industry to realize autonomous vehicles at a large scale, it must be able to sustain highway speeds safely and across different weather and driving conditions. Aeva’s LiDAR Tech Secures Strategic Partnerships With Industry Giants Aeva is getting a lot of attention because of its advanced LiDARs, inking deals with heavy hitters including Nvidia Corp. (NASDAQ: NVDA), Daimler Truck AG and Nikon Corp. (OTC: NINOY) and forging into new areas. The deal with Nvidia, the AI and graphics chip maker that boasts a market capitalization of about $2.90 trillion, holds the potential to validate Aeva’s technology. The two first began collaborating in the spring of 2022, when Aeva’s 4D LiDAR sensors were added to the NVIDIA DRIVE® Automotive platform. NVIDIA DRIVE is an open, end-to-end platform that enables automotive OEMs and developers to develop, train, validate and deploy safe self-driving technology at scale. The NVIDIA DRIVE platform consists of both the AI infrastructure and in-vehicle hardware and so ftware to deliver everything needed to develop autonomy at scale. Aeva delivers an advantage for perception in automated vehicles because it leverages per-point instant velocity information to detect and classify objects with higher confidence across longer ranges. “With Aeva as part of our DRIVE ecosystem network, we can provide customers access to this next generation of sensing capabilities for safe autonomous driving,” said Nvidia about Aeva at the time. Since then it has made inroads with OEMs, recently announcing some major deals. Take Aeva’s recent $1 billion deal with Daimler Truck AG as a prime example. Daimler Truck is using Aeva’s 4D LiDAR sensors in its Class 8 Freightliner Cascadia autonomous truck platform. Daimler Truck says it intends to integrate the LiDAR sensors directly into its production process, making it easy for customers to buy autonomous-ready trucks directly from its manufacturing plants. Daimler Truck said it chose Aeva’s LiDAR sensors because of their ability to provide enhanced safety and control. Production is slated to commence in 2026, according to Aeva. Daimler is aiming to have self-driving trucks on the road by 2027. “Daimler Truck is committed to leading the industry’s advancement toward autonomous trucks. Selecting the right LiDAR technology is a crucial strategic decision to safely deploy autonomous trucks on the road,” said Joanna Buttler, head of Global Autonomous Technology Group at Daimler Truck, when announcing the deal. “We are convinced that Aeva with its cutting-edge and reliable technology is the right production partner for LiDAR sensors and has the manufacturing capabilities to scale along with us,” she said. Growing Beyond Automotive Vehicles aren’t the only thing Aeva’s sensors are finding a home in. The company is also bringing its perception technology to security and AI based analytics, having been selected by a top U.S. National Security Organization to help protect critical energy infrastructure sites across the United States. Aeva’s sensors are expected to be the primary detection sensor to protect sensitive locations in various facilities from intrusion, such as water entries and exits and at perimeter fences. Aeva says after evaluating multiple sensing technologies, including 3D time-of-flight LiDAR, this top national defense security organization selected Aeva 4D LiDAR, further validating the growing applications for Aeva’s technology for some of the demanding and high-stakes physical security applications that can benefit from the application of sensing and AI. As a sign of having broadened and versatile applications, Aeva also inked a deal with Nikon, the global manufacturer and supplier of metrology and inspection equipment for the industrial automation and metrology markets. Aeva is producing sensors for Nikon industrial machines to inspect objects on manufacturing assembly lines for microscopic defects that can be smaller than the width of a human hair. This includes automobiles and aerospace components from some of the world’s largest manufacturers. Aeva is targeting to begin launching its sensors for the first industrial precision product with Nikon in the fourth quarter of 2024. “Today’s production win marks a significant milestone for Aeva in the growing field of automated manufacturing and it validates that Aeva’s unique FMCW technology goes well beyond automated driving with a perception platform powering the next wave of automation,” said Soroush Salehian, co-founder and CEO at Aeva when the deal was announced late last year. “We are excited to advance to our first commercial deployment with Nikon, a recognized leader in delivering high-precision industrial solutions of the highest quality, and look forward to leveraging our perception platform to bring additional programs to market.” Then there’s Aeva’s deal in railway for Germany’s rail sector initiative Digitale Schiene Deutschland. Aeva’s 4D LiDAR technology is being used in the group’s AutomatedTrain project, which is funded by the German Federal Ministry of Economic Affairs and Climate Action with collaboration from ten partners, including the world’s largest railway company Deutsche Bahn, Siemens Mobility and Bosch. The group aims to create and trial driverless, fully automated passenger trains by 2026. From vehicles to industrial security, manufacturing automation and trains, Aeva’s advanced sensors and perception suite seem to be finding their way into large and rapidly growing markets. Learn more about the latest on Aeva Technologies Inc. by checking out its recent quarterly results. Featured photo by Hyundai Motor Group on Unsplash Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 18, 2024 08:35 AM Eastern Daylight Time

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