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Revolutionary blockchain competition platform, Metawin, counts down to massive $1 million dollar prize draw

Metawin

Chainwire The countdown has begun as MetaWin, the pioneering blockchain competition platform, approaches the climax of its extraordinary MetaWin Millionaire event. With just 7 days remaining until the grand prize draw on December 22nd, 2023, the excitement is palpable. Time is Ticking: $1 Million USDC Awaits One Lucky Winner The highly anticipated MetaWin Millionaire prize draw is set to award one fortunate participant an astonishing $1 Million USDC (USD-based stable coin). The competition is scheduled to close its doors on December 22nd at 16:00 EST, leaving participants with just a week to secure their chance at this life-changing windfall. Influencers Amplify the Buzz The MetaWin Millionaire competition has sparked a viral frenzy across social media platforms, including X, where prominent influencers have taken the spotlight. Notably, the well-known NFT collector and Web3 ambassador, @Pranksy, boasting 440k followers, recently threw his hat into the ring, igniting a flurry of entries and heightened excitement. Blockchain Technology: Unveiling a New Era of Transparency MetaWin stands apart from traditional prize draws by operating on the Ethereum blockchain. This groundbreaking approach ensures that all users, entries, total contributions, and free entries are visible to the public. The winning Ethereum address will receive the prize within seconds of the draw’s conclusion, allowing the global community to witness the moment and congratulate the victor. Participants can continuously monitor their odds of winning until the competition’s final moments. Blockchain technology empowers MetaWin to lead the charge in transparency, redefining the landscape of competition platforms. Unlock Free Entries MetaWin Millionaire also offers a chance at victory without any financial commitment. Users can opt for the online free entry method by paying a nominal Ethereum network gas fee, allowing them to participate without contributing to the prize pool. Additionally, MetaWin’s smart contract system enables users to scale up their entries, affording multiple chances to win for the same gas fee as a single entry. Limited Time Remaining With the countdown clock ticking and the draw date fast approaching, MetaWin invites all potential participants to seize the moment and secure their opportunity to join the ranks of millionaires created by MetaWin. Users can claim their free entry today and hope for a life-altering win, via this link MetaWin’s official competition page today. MetaWin extends its best wishes to all entrants and anticipates celebrating alongside the fortunate victor. About MetaWin MetaWin stands at the forefront of on-chain competition platforms, revolutionizing the landscape of digital contests. Through harnessing the power of blockchain technology, MetaWin delivers a competition experience characterized by transparency, fairness, and excitement. With a track record of substantial giveaways and an unwavering commitment to innovation, MetaWin is shaping the future of online competitions. This article is provided for informational purposes only and is not intended to be construed as legal, financial, or tax advice. Readers should not rely solely on the information presented herein and should consult with their own legal, financial, or tax professionals regarding their specific situations. The author(s) and publisher make no representations or warranties concerning the accuracy or completeness of the information contained in this article. Reliance on any information provided in this article is solely at your own risk. Contact Details Metawin MetaWin Team press@metawin.inc

December 15, 2023 12:43 PM Eastern Standard Time

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Made-in-China.com “Special Exhibition” Event Concludes, Contributing to the Belt and Road Initiative

500NewsWire

China, Dec. 15, 2023 - ( 500NewsWire ) -- The recent Made-in-China.com “Special Exhibition” event, which led Chinese manufacturing companies to explore opportunities in Saudi Arabia and the UAE, has concluded. Online, Made-in-China.com built exclusive promotional pages for suppliers participating in the “Special Exhibition”. These pages showcased a diverse range of building materials and new energy products, strategically targeting buyers in the Middle East. Offline, Made-in-China.com organized Chinese companies to participate in local prominent exhibitions, conducted in-depth market research, visited local industrial parks for insights exchanges, and took part in the “Selected Sourcing Connect” conference. Saudi Arabia, as one of the pioneering supporters and participants of the Belt and Road Initiative, has witnessed a growing collaboration between the initiative and "Saudi Vision 2030". This alignment has resulted in an increased presence of Chinese companies in Saudi Arabia's infrastructure development projects. In Dammam, Saudi Arabia, the highly anticipated "Special Exhibition" kicked off, featuring the prominent participation of 40 Chinese enterprises led by Made-in-China.com at the Saudi International Construction & Interior Design Exhibition (CIDEX). This marked CIDEX's first opening to the Chinese market, with Made-in-China.com securing exclusive selling rights for the Chinese delegation and capturing core exhibition spaces, attracting widespread attention from exhibition attendees. Mr. Sayed Harunur Dashid, Project Manager at Habikon Trading & Gen Contracting, recently procured a batch of industrial electronic products through Made-in-China.com. He expressed, “Made-in-China.com helped me find satisfactory Chinese companies. If I were to rate their service on a scale of ten, I would give them a full ten! Whether in pre-sales or after-sales, there were dedicated personnel communicating with us, which made us very happy”. He also praised Made-in-China.com's search functionality for meeting his specific needs. At the exhibition site, “Special Exhibition” also drew attention from local Saudi media and government officials. Notably Abdulaziz Ahmed, the director of the Ministry of Industry and Mineral Resources in Saudi Arabia, made a special visit to the Made-in-China.com special exhibition to gain insights into the showcased products. Mr. Walid, Senior of CIDEX’s Exhibitions & Events Organizer, commented, “Made-in-China.com is quite an effective and easy way for connecting buyers with Chinese suppliers. One of the biggest advantages of manufacturing in China is that it's often low cost and of good quality, meeting the requirements of Saudi buyers”. The UAE, at the crossroads of the land and maritime Silk Road, was among the earliest countries to embrace the Belt and Road Initiative. As part of the “Special Exhibition”, Made-in-China.com not only participated in the renowned “Big 5” exhibition but also organized the “Selected Sourcing Connect in the UAE” conference at Hyatt Regency Dubai. Before the conference, a successful online matching process was implemented, connecting UAE buyers with Chinese enterprises. This innovative approach allowed for further targeted offline communications in Dubai. This approach effectively leveraged the strengths of Made-in-China.com both online and offline, facilitating global trade agreements. During the “Selected Sourcing Connect in the UAE” conference, Sarte Holdings LLC, a local real estate developer in Dubai, mainly procures materials related to energy-efficient construction. They engaged in in-depth negotiations with a new material company from Anhui Province during the conference. Sarte Holdings LLC expressed the intention to use WPC new materials in their upcoming projects. They have decided to conduct a second round of negotiations with the company after the Chinese New Year. A buyer with 40 years of trade experience in Dubai mentioned, “I purchased a spiral staircase through Made-in-China.com, and the quality is excellent, only at a quarter of the price in Europe”. By integrating online promotion, industry exhibitions, market research, industry exchanges, and buyer matchmaking, Made-in-China.com is innovatively combining business resources. In 2024, Made-in-China.com will focus on popular industries and international exhibitions, participating in events such as the Consumer Electronics Show, Hannover Messe, and the China Import and Export Fair (Canton Fair). Through online and offline full-service solutions, Made-in-China.com will continue to assist buyers in accurately finding Chinese suppliers. Contact Details Made-in-China.com buyerservice@made-in-china.com Company Website https://www.made-in-china.com/

December 15, 2023 12:00 PM Eastern Standard Time

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News Release

Massive Ripple (XRP) Projection by Van Winkle – Everlodge (ELDG) to Solve Key Issues in the $280T Real Estate Sector

Total Media

Crypto analyst that goes by Ripple Van Winkle on YouTube noted that the Ripple (XRP) crypto will see an influx of institutional money, and this, coupled with its deflationary properties could exponentially increase its price. Everlodge (ELDG) is also making significant waves among Web3 circles with its presale, as it solves key issues found in the $280 trillion real estate market that can make it a dominant force upon release. Today, we will dive into both projects to see how far they can rise, and will see what is the best cryptocurrency to invest in. Ripple (XRP) Nearly Breaks Past $0.70 – Can It Spike Above $1? XRP Right Now, the YouTube channel run by Ripple Van Winkle, recently uploaded a video going over how Ripple (XRP) can climb in value soon. Regulatory developments that will come in 2024 are seen as catalysts for this growth, as the Bitcoin exchange-traded fund (ETF) will pave the way for significant institutional investments. The analyst also cited comments made by Congressman Patrick McHenry predicting crypto regulations early next year. Throughout the past week, Ripple moved up in value from a low point of $0.60 to $0.69 and now needs to break past the $0.70 price barrier to reach new heights. In the past year, Ripple was up in value by a total of 58.4%. According to the Ripple price prediction, it can surge to $1.18 in 2024. Everlodge (ELDG) to Solve Key Issues in the Real Estate Sector Everlodge (ELDG) can disrupt the $280 trillion real estate market through solving key issues that have been a part of the industry for decades. Historically, most properties would cost millions of dollars in upfront capital, making them out of reach for most people. The market also lacks liquidity and transparency due to this. Everlodge will solve this by introducing blockchain technology that will lower the barrier of entry significantly. Properties will get minted as NFTs and will then be fractionalized into smaller pieces worth just $100 each. This way, anyone will be able to afford them, adding much-needed accessibility and liquidity to the market, as they can be resold at any time. Alongside this, the smart contract's metadata will store the ownership details, leading to higher transparency. The platform will even introduce a dedicated Launchpad, where builders can get funding from the community to build properties. Those who jump into these early can get access to high ROI opportunities. A Rewards Club will also be implemented, providing token holders with access to free nightly stays. Summary While Ripple will need some time to recover its value, analysts are still bullish on its future. Despite this, most traders are diversifying their holdings with Everlodge. Throughout its crypto ICO period, the ELDG token has reached Stage 8. Here, it is offered at $0.027. By solving issues such as liquidity, transparency, and accessibility, it will open up the real estate market to millions of people and can become a dominant force in the Web3 space, which could result in a major increase in the value of its native crypto. Visit Everlodge Contact Details Total Media Solutions media@Totalsolutionspr.io

December 15, 2023 12:00 PM Eastern Standard Time

Bitget Lists ALEX Lab (ALEX) On BTC Ecosystem Zone To Support Innovation In Crypto Landscape

Bitget

Chainwire Bitget, the world's leading cryptocurrency exchange and Web3 company, announces the inclusion of ALEX Lab (ALEX) in its Innovation Zone, BTC Ecosystem Zone and DeFi Zone, a pioneering platform in the Decentralized Finance (DeFi) space. This listing marks a significant expansion of Bitget's spot trading spectrum, underlining its commitment to support innovation in the ever-evolving crypto landscape. ALEX Lab, renowned as the first comprehensive DeFi services platform built on Bitcoin via the Stacks blockchain, is set to redefine the financial infrastructure on Bitcoin. Leveraging the unique capabilities of Stacks, ALEX Lab aims to enhance Bitcoin's functionality and reach, establishing a robust financial ecosystem. This groundbreaking project will also feature on Bitget's Launchpool, offering users an opportunity to maximize their returns and engage with the ALEX token in a more meaningful way. ALEX Lab operates under the governance of the ALEX Lab Foundation, a non-profit entity that plays a crucial role in overseeing the protocol's open-source technology. This foundation serves as a neutral platform for stakeholders to collaborate and reach consensus on the project's direction and development. Gracy Chen, Managing Director of Bitget, commented on the listing: " ALEX Lab stands out in the blockchain and cryptocurrency domain for its unique integration with the Bitcoin ecosystem through the Stacks blockchain. Its focus on DeFi services, combined with a structured approach to governance and tokenomics, positions it as an innovative and strategic player in the decentralized finance landscape. Bitget's commitment to embracing and promoting innovative digital assets and projects is reflected in our support for ALEX Lab, fostering development in the DeFi sector. Bitget's listing of ALEX Lab is more than just an expansion of its trading portfolio. represents a stride towards a future where DeFi and traditional finance converge, creating a more inclusive and innovative financial ecosystem." The inclusion of ALEX Lab is a testament to Bitget's strategic expansion and its dedication to diversifying investment opportunities for its users. Over the past three quarters of 2023, Bitget has significantly enriched its spot market offerings with over 255 new listings, providing unparalleled access to some of the most sought-after and valuable digital assets in the industry. Amidst this exhilarating profit spree, Bitget Launchpool served as a fertile ground for innovation, with 34 projects open for staking in the past nine months. For more information about the listing of ALEX Lab, please visit here. About Bitget Established in 2018, Bitget is the world's leading cryptocurrency exchange and Web3 company. Serving over 20 million users in 100+ countries and regions, the Bitget exchange is committed to helping users trade smarter with its pioneering copy trading feature and other trading solutions. Formerly known as BitKeep, Bitget Wallet is a world-class multi-chain crypto wallet that offers an array of comprehensive Web3 solutions and features including wallet functionality, swap, NFT Marketplace, DApp browser, and more. Bitget inspires individuals to embrace crypto through collaborations with credible partners, including legendary Argentinian footballer Lionel Messi and official eSports events organizer PGL. For more information, visit: Website | Twitter | Telegram | LinkedIn | Discord | Bitget Wallet For media inquiries, please contact: media@bitget.com Contact Details Rachel Cheung media@bitget.com

December 15, 2023 10:11 AM Eastern Standard Time

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Bitget Announces Listing of TonUP on Launchpad

Bitget

Chainwire Bitget, the world's leading cryptocurrency exchange and Web3 company, announced it will list the initial exchange offering (IEO) of the high-potential blockchain project TonUP on its Bitget Launchpad platform. TonUP is an outstanding Launchpad running on the TON blockchain dedicated to discovering and fostering projects that present new opportunities to the community. Since launching, TonUP has received support from the TON Foundation, TONcoin.Fund, and ForesightX. TonUP's mission is to support assets with great potential on TON and contribute to the ecosystem's development. During the commitment period, users can commit Bitget’s native token BGB to participate in the TonUP IEO. The BGB swap price will be announced after the holding calculation period ends. Upon closing the commitment window, TonUP tokens will be allocated to each user based on their committed BGB. Gracy Chen, Managing Director of Bitget, highlighted the company's commitment to supporting development across various blockchains and ecosystems, stating, "This project demonstrates TON's innovative potential and the support it offers, aligning with our dedication to providing users access to cutting-edge opportunities. Bitget has consistently expanded its market share in both spot and derivatives trading among centralized exchanges. The platform aims to provide valuable investment opportunities by diversifying its offerings." To participate in the TonUP launch on Bitget Launchpad, users can visit this link for more details. Bitget remains dedicated to advancing support for promising blockchain sector development. About Bitget Established in 2018, Bitget is the world's leading cryptocurrency exchange and Web3 company. Serving over 20 million users in 100+ countries and regions, the Bitget exchange is committed to helping users trade smarter with its pioneering copy trading feature and other trading solutions. Formerly known as BitKeep, Bitget Wallet is a world-class multi-chain crypto wallet that offers an array of comprehensive Web3 solutions and features including wallet functionality, swap, NFT Marketplace, DApp browser, and more. Bitget inspires individuals to embrace crypto through collaborations with credible partners, including legendary Argentinian footballer Lionel Messi and official eSports events organizer PGL. For more information, visit: Website | Twitter | Telegram | LinkedIn | Discord | Bitget Wallet For media inquiries, please contact: media@bitget.com Contact Details Rachel Cheung media@bitget.com

December 15, 2023 10:06 AM Eastern Standard Time

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Multifamily Leadership Names Sunbelt Properties as a Top-Ranked Employer in the Best Place to Work Multifamily® Awards

Sunbelt Properties

Sunbelt Properties today announced that it was awarded the #23 spot in the Best Places to Work Multifamily® rankings, and the #42 spot on the Best Places to Work Multifamily® for Women list, presented by Multifamily Leadership. The prestigious accolade was announced at the Multifamily Innovation® Summit in Phoenix, Arizona, held in early December. “We built Sunbelt Properties to improve the experience for the residents of the communities we serve,” said Danielle Miner, Chief Executive Officer of Sunbelt Properties. “We pride ourselves on a culture driven by passion and purpose, and we are proud of this important recognition, which belongs to our entire team.” According to Multifamily Leadership, the Best Places to Work Multifamily® initiative highlights companies that excel in creating and nurturing exceptional workplace cultures. As the multifamily industry evolves, property managers must focus on resident experience and employee engagement as crucial drivers for navigating various challenges and achieving sustained growth. To qualify for the Best Places to Work Multifamily® for Women list, companies must have a minimum of 15 women on their team, regardless of the organization's size. For organizations with more than 60 employees, at least 25% of the workforce should be women. A key factor is the female response rate to internal surveys, which must be 40% or higher, and even more stringent, at 80% for employers with fewer than 25 women. A minimum of 10 female responses is mandatory for consideration. Additionally, organizations must be recognized as a "Best Place to Work" for the current year and demonstrate an 80% average positive response rate among their female employees. For larger companies that conduct selective employee surveys, a minimum of 40% of respondents should be women. This comprehensive set of criteria underscores the importance of female representation and satisfaction in the workplace, highlighting the industry's commitment to fostering equitable and inclusive work environments. "The new era of leadership in the multifamily industry is defined by a commitment to making a positive societal impact,” said Patrick Antrim, Founder and CEO of Multifamily Leadership. “It's about understanding and being aligned with the company's mission and vision, and this alignment is increasingly vital as businesses are called upon to take on greater societal responsibilities. The Best Places to Work Multifamily® honorees are at the forefront of this movement, poised to shape the future with a stronger, more influential voice.” For detailed information and registration for the “Best Places to Work Multifamily®” program, visit www.multifamilyleadership.com/awards. About Sunbelt Properties Sunbelt Properties is a multifamily property management company focused on customer service and providing affordable apartment homes in Alabama, South Carolina, North Carolina, and Georgia. Our on-site management teams care about our residents. Our team is committed to providing safe, clean, enjoyable, and affordable communities throughout the southeast. For more information, please visit www.rentsunbelt.com. Contact Details For Sunbelt Properties infor@rentsunbelt.com Company Website https://www.rentsunbelt.com/

December 15, 2023 10:00 AM Eastern Standard Time

BNB Chain DEX THENA Integrates Orbs Liquidity Hub

Orbs

THENA, the liquidity protocol and DEX operating on BNB Chain, has announced the integration of Orbs Liquidity Hub. Powered by Orbs’ L3 technology, Liquidity Hub delivers lower fees, MEV protection, gasless transactions, and increased capital efficiency within a simplified UI. THENA has become the second DEX to integrate Orbs Liquidity Hub. A fully decentralized, permissionless, and composable DeFi protocol, Liquidity Hub is powered by the Orbs Network. It enables THENA traders to access the full spectrum of BNB Chain liquidity. Liquidity Hub sits as an optimization layer above the AMM. It taps into external liquidity for better price quotes and lower price impact. By drawing upon the full range of available on chain liquidity, Liquidity Hub delivers better pricing, allowing traders to maximize profits. If Liquidity Hub cannot execute a trade at a better price than the AMM, the transaction will return to the AMM contract and execute through the DEX as usual. The integration of Orbs Liquidity Hub into THENA follows the announcement of a recent funding round between the pair. Orbs has invested $600K into THENA to expand its core products and grow TVL, strengthening THENA’s position as a leading BNB Chain DEX. Orbs has also committed to providing technical solutions that will help THENA enhance on chain swaps to deliver better price efficiency and deeper liquidity. The addition of Orbs Liquidity Hub to THENA directly supports this goal. Orbs’ investment in THENA will be used to enhance user experience including the redevelopment of the protocol’s front-end. THENA also intends to grow its presence within the Asian market through increasing community outreach across the region. Orbs is on a mission to ensure projects on EVM chains can achieve their full potential. The integration of its Liquidity Hub with THENA moves Orbs closer to achieving this goal while ensuring that users on BNB Chain can extract greater value from every trade. About Orbs Orbs is an open, decentralized and public blockchain infrastructure. Its flagship products include TWAP and dLIMIT, limit order and TWAP protocols that are 100% decentralized and EVM compatible. They can be integrated with most DEXs and are currently live with exchanges such as QuickSwap, SpookySwap, Thena, and Chronos. Orbs is developed by a dedicated team of more than 30 people, with team members in Tel Aviv, London, New York, Tokyo, and Seoul. For more information, please visit www.orbs.com, or join our community at: Telegram: https://t.me/OrbsNetwork Twitter: https://twitter.com/orbs_network Contact Details Ran Hammer hello@orbs.com

December 15, 2023 10:00 AM Eastern Standard Time

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Shiba Inu (SHIB) & Retik Finance (RETIK) Under the Spotlight, What to Expect in 2024?

Prodigy Press Wire

As the crypto market grows, discerning the true value of digital assets becomes increasingly complex. Amid this evolving landscape, two tokens - Shiba Inu (SHIB) and Retik Finance (RETIK) - stand out as potentially the most undervalued tokens for 2024. This article explores the factors that contribute to a token being undervalued and how SHIB and RETIK are well-positioned to surpass these limitations. Understanding Undervaluation in the Cryptocurrency Market A token is considered undervalued when its market price is less than its intrinsic value. This discrepancy can arise due to various factors, including market sentiment, lack of awareness, or misunderstandings about the token's utility and potential. Undervalued tokens often offer a significant opportunity for investors, as their prices can increase once the market recognizes their true worth. Click Here To Take Part In Retik Finance Presale Shiba Inu (SHIB): More Than Just a Memecoin Shiba Inu started as a memecoin, a crypto asset that originally needed more clarity or purpose other than being part of a community-driven movement. However, SHIB has evolved significantly since its inception. Ecosystem Development: Shiba Inu is no longer just a meme token; it's developing its ecosystem, including a decentralized exchange (ShibaSwap), NFT projects, and a budding metaverse project. These developments add tangible utility to SHIB, extending its value beyond mere speculation. Strong Community Support: The SHIB community, known as the SHIBArmy, is a powerful force in the crypto world. This community's support and enthusiasm can drive adoption and increase demand for SHIB. Market Sentiment and Adoption: Despite its growing ecosystem, SHIB is often still viewed through the lens of its origins as a memecoin. This perception has kept its price relatively low compared to its potential, marking it as an undervalued token. Retik Finance (RETIK): An Emerging DeFi Powerhouse Retik Finance is a relatively new player in the DeFi space but has already shown significant promise. Further, Retik Finance sets itself apart as more than just a token. It aims to transform DeFi with user-friendly features like a DeFi wallet, swap services, and a DeFi debit card, connecting traditional finance with decentralized solutions. Utility and Features: RETIK, the native token of Retik Finance, is integral to its DeFi ecosystem. It facilitates transactions, governance, and various other functionalities within the platform. This utility is often overlooked, leading to its undervaluation. Innovative DeFi Solutions: Retik Finance aims to bridge the gap between traditional finance and DeFi. Its innovative solutions in areas like liquidity pools, staking, and decentralized lending position it as a valuable player in the DeFi space. Expert Predictions and Market Readiness: Unlike SHIB, which has huge tokens in circulation, Retik Finance is expected to have a more limited supply. This controlled distribution has the potential to create scarcity, thereby increasing demand. Experts predict that RETIK could surge by over 2000% before the year ends, fueled by its utility and the growth of the DeFi sector. $333k Mega Giveaway: Retik Finance is also running a significant giveaway, adding to its appeal. This giveaway not only attracts attention but also demonstrates the team’s confidence in the token's value and future. Further, Retik Finance has recently concluded its first stage of presale and has now progressed to stage 2. Priced at $0.040, the initial presale of Retik Finance has drawn significant attention, amassing a total of $842,815 at the time of writing. Click Here To Take Part In Retik Finance Presale The Undervaluation Factor: SHIB and RETIK Both SHIB and RETIK are currently undervalued for different reasons. For SHIB, it's a matter of evolving beyond its memecoin image, while for RETIK, it's about gaining recognition in a crowded DeFi market. However, both tokens possess strong fundamentals that could lead to significant price appreciation. Market Dynamics and Perception Shifts: As the market dynamics evolve and perceptions shift, both SHIB and RETIK stand to gain. For SHIB, broader adoption of its ecosystem could lead to a revaluation. For RETIK, increased awareness and understanding of its utility in the DeFi space could trigger a similar revaluation. Potential for Growth: Both SHIB and RETIK have substantial room for growth. SHIB's continued ecosystem development and RETIK's innovative DeFi solutions present opportunities for price appreciation as these developments gain traction and recognition. Investor Awareness and Smart Investing: As more investors become aware of the true potential of these tokens, demand is likely to increase. Smart investors are already taking positions, anticipating future gains based on the tokens' undervalued status. Conclusion: The Future Looks Bright for SHIB and RETIK SHIB and RETIK showcase interesting aspects, for investors seeking potential opportunities in tokens that may be undervalued. Each token brings unique features to its specific domain, with SHIB evolving from a meme to a utility token and RETIK making strides in the expanding DeFi market. As 2024 approaches, the potential for these tokens to appreciate is significant, driven by evolving market dynamics, growing ecosystems, and increased investor recognition of their true value. The combination of these factors and strategic initiatives like the Retik Finance giveaway positions SHIB and RETIK as smart investments for those looking to capitalize on undervalued assets in the crypto market. Click Here To Take Part In Retik Finance Presale Visit the links below for more information about Retik Finance (RETIK): Website: https://retik.com/ Linktree: https://linktr.ee/retikfinance Website: https://retik.com/ Linktree: https://linktr.ee/retikfinance Media contact Retik LLC Kingstown, Saint Vincent and the Grenadines Andrew Joel pr@retik.com This Press Release is for informational purposes only. The information does not constitute investment advice or an offer to invest. Neither the distribution company nor their partners are responsible for any decisions made as a result of the information presented. Any action taken upon the information on this Press Release is strictly at your own risk. Release ID: 838326

December 15, 2023 09:30 AM Eastern Standard Time

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A Look At Elicio Therapeutics’ (NASDAQ: ELTX) Pipeline: What Does This Cancer-Fighting Company Have In Store For The Future?

Benzinga

By Jeremy Golden, Benzinga Elicio Therapeutics Inc. (NYSE: ELTX) is using precision vaccines, immunomodulators and cell-based therapies to assemble cancer-killing immune responses against both blood and solid tumors. Founded in 2011, the company has developed an innovative pipeline of cancer immunotherapies addressing critical unmet needs. Three vaccine candidates are currently in Elicio Therapeutics’ pipeline: ELI-002, ELI-007 and ELI-008. ELI-002 is Elicio’s lead clinical program for Kirsten rat sarcoma (KRAS) driven cancers caused by a mutation of the KRAS gene. Designed to stimulate an immune response against the seven KRAS mutations driving 25% of solid tumors, ELI-002 is currently being studied in AMPLIFY-201, a phase 1 dose-escalation study. A structurally novel Amphiphilic (AMP) therapeutic vaccine, ELI-002 is comprised of AMP-modified mutant KRAS peptide antigens and ELI-004, an AMP-modified immune-stimulatory oligonucleotide CpG adjuvant. The AMP mKRAS peptides and AMP CpG are targeted to the lymph node, with the goal of enhancing the action of key immune cells. A new formulation, ELI-002 7P, is currently being studied in AMPLIFY-7P, a phase 1/2 trial in patients with high relapse risk mKRAS-driven solid tumors. The ELI-002 7P formulation is designed to provide immune response coverage against seven of the most common KRAS mutations. This is increasing the prospective patient population for ELI-002 while potentially reducing the chance of bypass resistance mechanisms. Pre-Clinical Programs Elicio Therapeutics’ product candidate for BRAF-driven cancers, ELI-007 is a multivalent lymph node-targeted AMP-peptide vaccine directed at BRAF V600E mutations, which are present in 40% of melanoma, 10% of colon cancer and 2% of lung cancer diagnoses. Present-day small molecule inhibitors generate initial responses in BRAF V600E-mutated melanoma. These responses, however, are not sustained because of resistance due to alternative growth signaling pathways and the fact that few initial responses occur in BRAF-mutated colon cancer. ELI-007 draws on previous research and pre-clinical trial data that has shown that T cells can respond to the driver mutation V600E in BRAF. The transfer of tumor-infiltrating lymphocytes that recognize mutated BRAF resulted in a durable complete response in a recent case study. The fact that the protein expression of BRAF V600E is maintained at high levels in these tumors suggests that they would be susceptible to T cells that are specific for the mutated BRAF. Like the KRAS mutations causing the type of cancer that ELI-002 aims to combat, mutations in p53 are found in a large number and wide variety of cancers, accounting for approximately 60% of patients with solid tumors. An AMP-peptide vaccine targeting p53 hotspot mutations could potentially expand and mature tumor-specific T cells through enhanced delivery and immune stimulation in draining lymph nodes to generate tumor-specific immunity capable of eliminating tumor tissue. That is the approach of ELI-008, which stands out as a multivalent lymph node-targeted AMP-peptide vaccine directed at p53 hotspot mutations. ELI-008 is being developed to target hotspot mutations in p53 in solid tumors including colorectal cancer, melanoma and non-small cell lung cancer (NSCLC). Elicio Therapeutics is leading the charge toward treating cancer through vaccination. By combining expertise in immunology and immunotherapy, Elicio is precisely targeting and fully engaging the lymph nodes, the site in our bodies where the immune response to cancer is orchestrated. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

December 15, 2023 09:15 AM Eastern Standard Time

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