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Nuvectis Pharma Rises in Pre-Market Following FDA Orphan Drug Designation for NXP800, Fueling Optimism Ahead of Key Clinical Data

Global Markets News

Nuvectis Pharma (NASDAQ: NVCT) has achieved a significant milestone with the U.S. Food and Drug Administration (FDA) granting Orphan Drug Designation for its lead candidate, NXP800. This designation, specifically for the treatment of ARID1a-deficient ovarian, fallopian tube, and primary peritoneal cancers, marks a critical step forward in Nuvectis’s mission to address unmet needs in oncology. Orphan Drug Designation: A Strategic Advantage The FDA’s Orphan Drug Designation is awarded to drugs that show promise in treating rare diseases affecting fewer than 200,000 people in the U.S. For Nuvectis, this designation not only validates the potential of NXP800 but also provides several strategic benefits. These include tax credits for clinical trial costs, exemption from certain FDA fees, and potentially seven years of market exclusivity upon approval. NXP800 targets ARID1a-deficient cancers, a subset of ovarian cancers that present significant treatment challenges. The Orphan Drug Designation underscores the importance of this candidate in potentially offering a new, more effective treatment option for patients with this specific genetic mutation. Background and Market Impact This latest achievement builds on Nuvectis Pharma’s earlier successes. Earlier this year, the FDA granted Fast Track Designation to NXP800 for its development in platinum-resistant, ARID1a-mutated ovarian cancer. The Fast Track status, combined with the Orphan Drug Designation, highlights the urgent need for innovative treatments in this space and positions NXP800 as a potential game-changer in oncology. Financial analysts have taken note of Nuvectis’s progress. H.C. Wainwright recently reiterated its buy rating for Nuvectis, setting a price target of $21. This optimistic outlook reflects the market’s confidence in the company’s strategic direction, particularly as it prepares to release key clinical data later this year. Anticipation for Upcoming Results The next few months are expected to be pivotal for Nuvectis Pharma. The company is poised to share updates from its ongoing Phase 1b clinical trial of NXP800, which targets patients with platinum-resistant, ARID1a-mutated ovarian cancer. This trial is being closely watched, as positive results could significantly advance the development of NXP800, bringing it closer to pivotal trials and eventual regulatory approval. Additionally, Nuvectis is also conducting a Phase 1a dose escalation study for NXP900, its second key candidate, which targets YES1/SRC-driven tumors. Updates from this study are expected to provide further insights into the safety and potential efficacy of NXP900. ### Nuvvectis' Full announcment, titled " Nuvectis Pharma Announces Orphan Drug Designation Granted by the FDA for NXP800 for the Treatment of ARID1a-deficient Ovarian, Fallopian Tube, and Primary Peritoneal Cancers" was published on August 29th, 2024. ### This article is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. https://justpaste.it/fcm9n/pdf. Global Markets News Network is a commercial digital brand compensated to provide coverage of innovative companies and industries and it is thus subject to conflicts of interest. Contact Details Global Markets News News Coverage ronald@futuremarketsresearch.com

August 29, 2024 08:20 AM Eastern Daylight Time

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How Seniors Can Benefit from Flip Phones

Spark Metro

In a world increasingly dominated by smartphones and constant connectivity, the simplicity of flip phones remains a compelling choice, particularly for seniors. While modern smartphones offer a multitude of features, their complexity can often be overwhelming for those who prioritize ease of use and straightforward functionality. For seniors, the balance between staying connected and maintaining simplicity is crucial, making flip phones an ideal solution. This article explores the many advantages of flip phones for seniors, highlighting how these devices offer a perfect blend of traditional simplicity and modern technology. The Appeal of Simplicity One of the most significant advantages of flip phones for seniors is their simplicity. Unlike smartphones, which require navigating complex menus and apps, flip phones offer a more straightforward interface. The act of flipping open the phone to answer a call and closing it to hang up is intuitive and familiar, providing a sense of nostalgia and comfort to many users. This simplicity reduces the learning curve, allowing seniors to use their phones confidently without needing extensive technical knowledge. Moreover, the tactile buttons on flip phones are often larger and more spaced out than those on smartphones, making them easier to press. This is particularly important for seniors who may struggle with dexterity or have vision impairments. The physical feedback of pressing a button, as opposed to the touchscreens of smartphones, adds to the ease of use, ensuring that seniors can make calls and send texts with minimal frustration. Enhanced Security and Privacy Another key advantage of flip phones for seniors is the enhanced security and privacy they offer. Smartphones are often vulnerable to various security threats, from phishing scams to malware, due to their internet connectivity and app usage. In contrast, flip phones have limited internet capabilities, significantly reducing the risk of cyber threats. For seniors who may not be as tech-savvy or aware of online risks, this limitation becomes a protective feature. Furthermore, flip phones typically do not store as much personal information as smartphones, which decreases the potential impact of losing the device. Seniors can feel more secure knowing that their personal data is less likely to be compromised if their phone is misplaced or stolen. This peace of mind is invaluable for those who prioritize security and privacy. Superior Battery Life Battery life is another area where flip phones excel, making them particularly well-suited for seniors. Smartphones are notorious for their relatively short battery life, often requiring daily charging due to their power-hungry apps and features. On the other hand, flip phones are designed with efficiency in mind, and their limited features contribute to significantly longer battery life. For seniors, the ability to go several days without needing to charge their phone is a major advantage. It reduces the hassle of constantly monitoring battery levels and ensures that their phone is always ready for use, particularly in emergencies. This reliability is a crucial factor for seniors who may not want to worry about their phone dying at an inconvenient time. Durability and Robust Design Flip phones are also known for their durability, a feature that is particularly important for seniors. The robust design of flip phones makes them less susceptible to damage from drops and other accidents, which are common concerns for users of all ages. The clamshell design not only protects the screen when the phone is closed but also adds a layer of protection against everyday wear and tear. This durability means that seniors can use their flip phones for extended periods without the need for frequent repairs or replacements. The sturdy construction of flip phones also makes them easier to handle, reducing the likelihood of accidental drops. For seniors, the combination of durability and ease of use ensures that their phone remains a reliable companion in their daily lives. Choosing the Right Flip Phone When selecting a flip phone for a senior, it's essential to consider specific features that cater to their needs. User-friendly features, reliable service, and a robust design are all critical factors to ensure that the phone meets their requirements. For instance, the Consumer Cellular IRIS Flip is an excellent option for seniors, offering a range of features designed with ease of use in mind. The large, easy-to-read display, intuitive navigation, and enhanced sound quality make it particularly suitable for those with vision or hearing impairments. Additionally, the IRIS Flip includes emergency response features, providing an added layer of security for seniors who may need assistance quickly. Its durable design ensures that it can withstand daily use, while the extended battery life means that seniors can rely on their phone to be ready when they need it most. The Importance of Reliable Service In addition to selecting a phone with the right features, it's also crucial to choose a provider that offers reliable service. For seniors, having a dependable network is essential for staying connected with family, friends, and emergency services. When considering a flip phone, ensure that the provider offers strong coverage in your area and has a reputation for excellent customer service. A good provider will also offer flexible plans that cater to the needs of seniors, such as low-cost options for those who primarily use their phone for calls and texts. This flexibility ensures that seniors are not paying for features they do not need, making their phone plan more affordable and tailored to their usage patterns. The Modern Benefits of a Traditional Design While flip phones may seem like a relic of the past, they continue to offer significant advantages in the digital age, especially for seniors. Their simplicity, enhanced security, superior battery life, and durability make them an attractive option for those who value straightforward, reliable communication. In addition to these benefits, modern flip phones have incorporated certain technological advancements that enhance their functionality without compromising their user-friendly design. Features such as voice commands, text-to-speech, and enhanced sound quality have been integrated into many flip phones, providing seniors with the convenience of modern technology while maintaining the simplicity they prefer. Conclusion For seniors, the choice of a mobile phone should prioritize ease of use, reliability, and security. Flip phones, with their intuitive design and practical features, offer a compelling solution that meets these needs. While smartphones dominate the market with their endless apps and features, the straightforward nature of flip phones provides a refreshing alternative, ensuring that seniors can stay connected without the complexity and distractions of more advanced devices. The Consumer Cellular IRIS Flip exemplifies the best of both worlds, combining the simplicity of a flip phone with carefully selected modern features that enhance usability and safety. By choosing the right flip phone, seniors can enjoy the benefits of staying connected while maintaining control over their digital experience. Contact Details Alex +1 302-597-6768 Apexreviews154@gmail.com

August 27, 2024 03:52 AM Eastern Daylight Time

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Navigate your Investment Roadmap with Select Sector SPDR ETFs

Select Sector SPDR

In an era where market dynamics shift as swiftly as the winds, Select Sector SPDR ETFs remain a beacon for investors aiming to harness the potential of sector-specific investments. Tailored to meet the diverse needs of both individual and institutional investors, these ETFs chart a course for strategic portfolio management by distilling the vast S&P 500 into accessible segments. Focused Investment Across Diverse Sectors Select Sector SPDR ETFs stand out by offering a focused approach to investing, breaking down the broad landscape of the S&P 500 into key sectors. This segmentation allows investors to pinpoint their investments according to specific economic areas, aligning their portfolios with their investment goals, risk assessments, and market perspectives. Below is a glimpse into the diverse holdings that form the core of the Select Sector SPDR ETFs: Communication Services Select Sector SPDR Fund (XLC): Zooms in on the telecommunications and media sectors, capturing the pulse of digital communication. Consumer Discretionary Select Sector SPDR Fund (XLY): Targets the vibrant consumer goods and services sector, from retail giants to entertainment behemoths. Consumer Staples Select Sector SPDR Fund (XLP): Focuses on essential consumer goods and services, providing stability in fluctuating markets. Energy Select Sector SPDR Fund (XLE): Powers through with a dedicated look at the energy sector, from fossil fuels to renewable resources. Financials Select Sector SPDR Fund (XLF): Encompasses the robust banking, investment, and insurance industries, the backbone of economic infrastructure. Health Care Select Sector SPDR Fund (XLV): Centers on the pharmaceuticals, healthcare equipment, and services sectors, addressing global health needs. Industrials Select Sector SPDR Fund (XLI): Broadens the horizon with manufacturing, construction, and logistics firms. Materials Select Sector SPDR Fund (XLB): Covers the foundational chemicals, construction materials, and packaging industries. Real Estate Select Sector SPDR Fund (XLRE): Opens doors to commercial real estate services and REITs. Technology Select Sector SPDR Fund (XLK): Accelerates into the information technology and electronics sectors, powering innovation and connectivity. Utilities Select Sector SPDR Fund (XLU): Illuminates the path with utility companies, ensuring the flow of essential services. A Path for Strategic Investment By offering a lens through which to invest in specific sectors, Select Sector SPDR ETFs enable investors to steer their portfolios with confidence and clarity. The ETFs’ commitment to transparency and strategic focus empowers investors to adapt and thrive amidst the ebb and flow of market conditions. In the evolving landscape of the financial markets, Select Sector SPDR ETFs stand as a testament to the power of targeted investment. Through detailed sector analysis and dedicated portfolio exposure, these ETFs offer a distinguished pathway for those seeking to refine their investment strategies with sector-specific allocations. About Select Sector SPDR ETFs Select Sector SPDR ETFs are a series of exchange-traded funds designed to provide investors with an effective way to engage in sector-specific investment strategies. By segmenting the S&P 500 into distinct sectors, Select Sector SPDR ETFs furnish investors with the tools necessary for targeted and strategic investment decisions. DISCLAIMER: This is a work of research and should not be taken as investment or financial advice. Therefore, Select Sector SPDRs or the publisher is not liable for any decision made based on the publication. About the Company: Select Sector SPDR ETFs offer flexibility and customization opportunities. Many investors have similar outlooks, but no two are exactly alike. Select Sector SPDR ETFs let investors select the sectors that best meet their investment goals. DISCLOSURES The S&P 500 Index is an unmanaged index of 500 common stocks that is generally considered representative of the U.S. stock market. The index is heavily weighted toward stocks with large market capitalizations and represents approximately two-thirds of the total market value of all domestic common stocks. The S&P 500 Index figures do not reflect any fees, expenses or taxes. An investor should consider investment objectives, risks, fees and expenses before investing. One may not invest directly in an index. Transparent ETFs provide daily disclosure of portfolio holdings and weightings All ETFs are subject to risk, including loss of principal. Sector ETF products are also subject to sector risk and nondiversification risk, which generally will result in greater price fluctuations than the overall market. Diversification does not eliminate risk. An investor should consider investment objectives, risks, charges and expenses carefully before investing. To obtain a prospectus, which contains this and other information, call 1-866-SECTOR-ETF (732-8673) or visit www.sectorspdrs.com. Read the prospectus carefully before investing. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is distributor for the Select Sector SPDR Trust. Media Contact: Company: Select Sector SPDRs Contact: Dan Dolan* Address: 1290 Broadway, Suite 1000, Denver, CO 80203 Country: United States Email: dan.dolan@sectorspdrs.com Website: https://www.sectorspdrs.com/ *Dan Dolan is a Registered Representative of ALPS Portfolio Solutions Distributor, Inc. ALPS Portfolio Solutions Distributor, Inc., a registered broker-dealer, is the distributor for the Select Sector SPDR Trust. SEL007734 EXP 10/31/24 Contact Details Dan Dolan +1 203-935-8103 dan.dolan@sectorspdrs.com Company Website https://www.sectorspdrs.com/

August 22, 2024 05:00 AM Eastern Daylight Time

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COMCAST RISE, A NATIONAL INITIATIVE TO SUPPORT AND STRENGTHEN SMALL BUSINESSES, AWARDS ANOTHER 100 HOUSTONIANS WITH COMPREHENSIVE GRANT PACKAGES

Comcast Texas

Today, Comcast announced the 100 businesses in the Greater Houston area that will receive comprehensive grant packages, which include business consultation services, educational resources, a $5,000 monetary grant, creative production, media schedule, and a technology makeover. The recipients are among more than 14,000 entrepreneurs nationwide who have been selected through the Comcast RISE program to date. Comcast RISE is committed to supporting the growth of all small businesses, while advancing the objectives of diversity, equity, and inclusion, as well as community investment. The program was created to help businesses and their communities thrive, with a focus on economic growth. The regions in this round included Atlanta, Houston, Jacksonville, Richmond, VA and southern Colorado. 100 grants per city, or 500 grants overall, were announced today and will be awarded in September 2024. A sample of Houston’s grant recipients include Red Circle Ice Cream in southwest Houston, and Miyagi Ken International Karate Academy in Spring. “I’m speechless. As a small business, this means the world to us,” said Nickey Ngo, owner of Red Circle Ice Cream. “We’re a small mom and pop ice cream shop, doing everything by ourselves. I feel like I won the lottery. Comcast RISE will help grow my business and keep up with the competition.” “Supporting small businesses means investing in the heart of our communities,” said Loren Hudson, SVP and Chief Diversity Officer, Connectivity and Platforms, Comcast. “By empowering entrepreneurs and small business owners with the skills and resources they need to grow and succeed, we help ensure our local neighborhoods can flourish and thrive too.” Comcast RISE was created in November 2020 to help small businesses hardest hit by COVID-19, from bakeries and barber shops to childcare centers and cleaning services, by providing the grants needed to survive and recover. The program has evolved from helping businesses survive the pandemic, to helping businesses and their communities thrive with a focus on economic growth. Grant packages include: COACHING SESSIONS - Business assessment and coaching that provide business owners with recommendations on how to help grow their businesses. EDUCATION RESOURCES - 12-month access to online entrepreneurship courses, learning modules and resources for small business owners. MONETARY GRANT - $5,000 monetary grant. CREATIVE PRODUCTION & MEDIA – Professionally produced 30-second TV commercial, plus a media strategy consultation and a 180-day linear media schedule. (Taxes and other fees may apply for production and media services.) TECHNOLOGY MAKEOVER - Computer equipment and Internet, Voice and Cybersecurity services for 12 months. (Taxes and other fees may apply for tech makeover services.) In addition, any small business owner can visit the Comcast RISE destination on X1 featuring aggregated small business news, tips, insights, and more. X1 customers can say “Comcast RISE” into the voice remote. Comcast RISE is part of Project UP, the company’s $1 billion commitment to advance digital equity through programs and community partnerships that connect people to the Internet, advance economic mobility and open doors for the next generation of innovators, entrepreneurs, storytellers and creators. More information is available at www.ComcastRISE.com. Comcast Corporation (Nasdaq: CMCSA) is a global media and technology company. From the connectivity and platforms we provide, to the content and experiences we create, our businesses reach hundreds of millions of customers, viewers, and guests worldwide. We deliver world-class broadband, wireless, and video through Xfinity, Comcast Business, and Sky; produce, distribute, and stream leading entertainment, sports, and news through brands including NBC, Telemundo, Universal, Peacock, and Sky; and bring incredible theme parks and attractions to life through Universal Destinations & Experiences. Visit www.comcastcorporation.com for more information. Contact Details Ilona Carson +1 346-624-2074 ilona_carson@comcast.com Company Website https://houston.comcast.com/

August 13, 2024 11:06 AM Central Daylight Time

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Personalized Learning With AI – This Company Is Delivering Results Globally

Benzinga

By Johnny Rice, Benzinga Roger Hamilton, CEO of Genius Group (AMEX: GNS), was recently a guest on Benzinga’s All-Access. Genius Group is a leading provider of AI-powered, digital-first education solutions that is attempting to disrupt the highly standardized system of traditional education with a personalized, flexible and life-long learning curriculum for the modern student. The company recently announced that it has secured a $22 million ‘Genius Nation’ contract with the Government of the Republic of Kazakhstan, enabling the development of a Sovereign AI in the country. Learn more here: Featured photo by dlxmedia.hu on Unsplash. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

August 13, 2024 08:50 AM Eastern Daylight Time

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Back to School Ready 2024

News Media Group, Inc.

Contact Details News Media Group, Inc. Karl Wayne +1 334-440-6397 karl@newsmg.com Company Website https://newsmg.com/

August 08, 2024 01:33 PM Eastern Daylight Time

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NAVEX to Demystify IT Risk Communication at ISACA GRC Conference

NAVEX Global

NAVEX, the global leader in integrated risk and compliance management software, will deliver a key session at the upcoming ISACA Governance, Risk, and Control (GRC) Conference in Austin, Texas, August 12-14, 2024. The session, " Getting Our Wires Crossed: How to Speak IT Risk as a Compliance Professional," will be presented by Kyle Martin, Vice President of GRC Solutions at NAVEX, and Robert Clark, Chief Audit and Compliance Officer at Howard University. In an era where cybersecurity threats and regulatory pressures are at an all-time high, the ability to effectively communicate IT risks across organizational silos has become a critical skill for compliance professionals. Attendees can join the session, CS 7–4, on August 13th at 11:00 to gain valuable insights into: Understanding and translating risk and compliance terminology. Evaluating program maturity levels and their organizational implications. Assessing risks and controls across all business facets, including third-party risk management. Crafting compelling IT risk reports for executive teams and board directors. "In today's interconnected business environment, the ability to translate IT risk insights into compelling narratives for CEOs is no longer optional—it's essential," said Kyle Martin. "As a result, this session aims to empower compliance professionals with the tools they need to navigate this critical intersection confidently." The ISACA GRC Conference, now in its 11th year, brings together leading minds in governance, risk management, and control to provide world-class content and practical guidance. NAVEX's participation underscores its commitment to advancing the field of integrated risk and compliance management. For more information about NAVEX's participation in the ISACA GRC Conference 2024 or to schedule an interview with the speakers, please contact Senior Public Relations Manager, Scott Levesque at scott.levesque@navex.com. NAVEX is trusted by thousands of customers worldwide to help them achieve the business outcomes that matter most. As the global leader in integrated risk and compliance management software and services, we deliver solutions through the NAVEX One platform, the industry’s most comprehensive governance, risk and compliance (GRC) information system. For more information, visit NAVEX.com and our blog. Follow us on Twitter and LinkedIn. Contact Details Navex Global scott.levesque@navex.com Company Website https://navex.com

August 06, 2024 08:00 AM Eastern Daylight Time

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What’s Cool for School 2024

News Media Group, Inc.

Contact Details Karl Wayne +1 334-440-6397 karl@newsmg.com Company Website https://newsmg.com/

August 01, 2024 01:10 PM Eastern Daylight Time

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Players Health Partners with RealResponse to Enhance Athlete Safety and Wellbeing Through Real-Time Reporting

Players Health

Players Health, the leading provider of athlete safety and insurance solutions, today announced a partnership with RealResponse, a powerful web-based platform where athletes can anonymously report improper conduct through confidential two-way dialogue. Together, the two industry leaders will implement an innovative reporting platform for over five million athletes, leagues, and organizations in the Players Health specialty youth sports insurance ecosystem. This collaboration will blend RealResponse’s multi-channel communication technology into Players Health's sports-centric insurance, education, training, and compliance offerings, empowering kids, parents, guardians, and coaches to share feedback, ask questions, and access resources anonymously and in real-time. The RealResponse platform has already proven effective in facilitating rapid communication across amateur athletics, offering real-time anonymous visibility into critical situations, allowing for timely support for mental health needs. “Everything we do is centered around creating the safest and most accessible environments for amateur athletes to play the sports they love. RealResponse’s integration into our growing community allows us to provide our clients with the protected and secure communication tools needed to achieve clarity when investigating incidents,” said Tyrre Burks, CEO & Founder of Players Health. “This partnership creates a crucial framework for our clients to manage risk effectively and act promptly on valuable feedback.” As part of this partnership, Players Health becomes a preferred insurance, health and safety provider for RealResponse, ensuring that youth sports organizations have access to comprehensive coverage alongside innovative reporting solutions. Conversely, RealResponse will serve as a preferred feedback and anonymous reporting platform for Players Health, reinforcing its commitment to athlete safety and proactive risk management. This strategic alignment will enhance the resources available to organizations, and help foster a culture of safety and accountability across the youth sports ecosystem. “Players Health and RealResponse are committed to empowering amateur sports and educational institutions with innovative technological solutions that resonate with today's youth,” said David Chadwick, Founder and CEO of RealResponse. “By utilizing preferred communication channels—such as text, QR codes and WhatsApp—we're taking significant strides to prevent abuse and misconduct. Our advanced, seamless auto-routing capabilities streamline administrative processes, making it easier for organizations to uphold safety standards while supporting Players Health’s expanding network of clients.” Learn more about the partnership here: https://www.playershealth.com/ Players Health is a sports technology company providing digital risk management services, reporting tools and insurance products to sports organizations to empower them to stay ahead of their ever-changing safety and compliance responsibilities. Working towards establishing the safest environment for athletes, Players Health views the health and safety of athletes as a priority in today's sports landscape. ABOUT REALRESPONSE RealResponse is committed to elevating all voices in sports. The RealResponse community includes more than two million athletes, coaches, administrators, and staff, across college and professional sports, governing bodies, youth organizations, and integrity units. Founded in 2015, RealResponse empowers organizations and individuals to operate confidently in the high-risk world of sports – with real-time, two-way anonymous communications, surveys, compliance support, and data. For more information, visit realresponse.com. Contact Details Digital Sport by Hot Paper Lantern Jackson Gaskins playershealth@hotpaperlantern.com Company Website https://www.playershealth.com

July 24, 2024 08:00 AM Eastern Daylight Time

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