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Industry Update: 3 Exciting Precision Oncology Players to Watch Following Summit’s Meteoric Rise: Silexion, Nuvectis, Scorpian

Global Markets News

Summit Therapeutics (NASDAQ: SMMT) recently captured headlines with the release of its Phase 3 data for ivonescimab, a targeted NSCLC therapy that has generated substantial buzz. The results from its trial conducted in China showed a dramatic 49% reduction in the risk of disease progression or death compared to Merck’s Keytruda, signaling a potentially disruptive force in NSCLC treatment. However, the news wasn’t without its concerns—since the trial data originates from China, there are questions about its applicability to broader, global populations. As noted by BMO Capital Markets’ Evan Seigerman: “Results may or may not be generalizable beyond the China-focused patient population initially assessed.” Despite this, Summit’s valuation has risen by over 100%, now approximating $19 billion. With such a high valuation, the company could see limited room for further significant gains, leading many in the industry to explore other emerging opportunities in precision oncology. Alongside Summit, there are quite a few other players in the field. Some if these companies have even already shown promising initial results and could see similar success in the future if they were to report positive results. These emerging players are worth watching for those interested in following precision oncology drug candidates and pipelines. Among them are precision oncology innovators such as Silexion Therapeutics, Nuvectis Pharma, and Scorpion Therapeutics, which we discuss below. Silexion Therapeutics: Disrupting the KRAS-Driven Cancer Space Silexion Therapeutics (NASDAQ: SLXN) is another under-the-radar player in the precision oncology space, with a focus on KRAS-driven cancers—a notoriously difficult target in oncology. While current small-molecule KRAS inhibitors are making progress, they are often limited to specific mutations, such as KRAS G12C, which accounts for a small percentage of cancers. Silexion’s RNA interference (RNAi) approach offers a broader solution, targeting a wider spectrum of KRAS mutations, particularly in pancreatic cancer, one of the deadliest and most treatment-resistant cancers. At the heart of Silexion’s approach is its LODER™ platform, which delivers siRNA directly to the tumor site, silencing KRAS mutations at the genetic level. This localized delivery not only increases efficacy by concentrating the treatment in the tumor, but it also reduces systemic side effects. Silexion’s next-generation candidate, SIL-204, is an optimized siRNA formulation designed to target pan-KRAS G12x mutations, positioning it to treat a broader range of KRAS-driven cancers beyond pancreatic cancer, such as lung and colorectal cancers. In Phase 2 trials for locally advanced pancreatic cancer, Silexion's LODER™ platform showed a 9.3-month improvement in overall survival when combined with standard chemotherapy. Additionally, the objective response rate (ORR) increased from 20% with chemotherapy alone to 55% with the combination, and in some cases, tumors that were initially non-resectable became operable after treatment with LODER™. These results are especially encouraging given the limited options available for pancreatic cancer patients. SIL-204, is expected to enter Phase 2/3 clinical trials in 2025-2026. What makes Silexion particularly intriguing is its current market valuation. Valued at aproximatly just ~$9 million following its SPAC merger, the company’s valuation could be perceived as low when compared to some of its peers, especially given its innovative technology and promising clinical achievements. Some have wondered whether this low valuation has more to do with dynamics post-SPAC companies. If Silexion can report positive results in its later-stage trials, the company’s outlook could dramatically improve, reflecting the potential of its RNAi-based platform. Like NXP900, SIL-204 could potentially have vast applications across multiple KRAS-driven cancer types, making Silexion a company to watch closely as it advances through clinical development. Nuvectis Pharma: Targeting NSCLC and Beyond by Inhibiting SRC/YES1 Kinases Nuvectis Pharma (NASDAQ: NVCT) has been quietly making strides in the precision oncology sector, developing innovative therapies aimed at overcoming treatment resistance in hard-to-treat cancers. Its lead candidate, NXP900, targets NSCLC by inhibiting the SRC/YES1 kinases, which play critical roles in cancer cell survival and resistance to current therapies. This approach positions NXP900 as a potential game-changer in the treatment of NSCLC, particularly in patients who have developed resistance to EGFR and ALK inhibitors, such as AstraZeneca’s Tagrisso and Novartis’ Alecensa. NXP900 is still in the early stages of clinical development, currently undergoing Phase 1 trials. However, preclinical studies have already shown that it has strong anti-tumor activity in resistant NSCLC models. Even more promising is its potential application beyond NSCLC. Like Summit's ivonescimab, NXP900 focuses on resistance, but it also has broader applications due to its ability to target multiple cancer types driven by SRC/YES1 pathways. This versatility makes it a promising asset not just for NSCLC but also for other difficult-to-treat cancers like squamous cell carcinomas. In addition to NXP900, Nuvectis is advancing NXP800, another precision oncology candidate that is further along in the clinical development process. NXP800 is currently in Phase 1b trials, targeting ARID1a-mutated cancers such as ovarian and endometrial cancers. The early clinical data for NXP800 is promising, showing positive responses in patients with platinum-resistant ovarian cancer. With two strong candidates in the pipeline, Nuvectis is positioning itself as a formidable player in the precision oncology landscape. As Summit’s ivonescimab continues to gain attention, Nuvectis’ earlier-stage NXP900, with its NSCLC focus and beyond, could see similar success in the future if clinical results continue to trend positively. Scorpion Therapeutics: Pioneering Mutant-Selective Therapies Scorpion Therapeutics is redefining the frontier of precision oncology with its focus on delivering highly selective small molecules targeting validated and previously undruggable cancer mutations. Its lead candidate, STX-478, is a mutant-selective, allosteric PI3Kα inhibitor currently in Phase 1/2 trials for advanced solid tumors. Early data presented at the ESMO Congress 2024 highlighted its potential, with STX-478 demonstrating a 23% overall response rate in breast cancer and a 21% response rate across all tumor types, positioning it as a potentially best-in-class PI3Kα inhibitor. STX-478 is notable for its ability to spare wild-type PI3Kα activity in normal tissues, avoiding the toxicities seen with previous PI3Kα inhibitors, such as hyperglycemia and rash. Tumor reductions were seen in 72% of patients treated with STX-478 as a monotherapy, with circulating tumor DNA levels dropping in 86% of patients. This mutant-selective precision could help overcome the limitations of existing PI3Kα inhibitors, which have struggled with dose-limiting toxicities. In July 2024, Scorpion raised $150 million in a Series C financing round, co-led by Frazier Life Sciences and Lightspeed Venture Partners. The additional funding will support the advancement of STX-478 and other pipeline assets, positioning Scorpion for further clinical success. Scorpion’s pipeline includes a broad range of wholly-owned compounds that target both validated and novel cancer targets, positioning the company for future expansion into larger patient populations. As STX-478 progresses through clinical development, Scorpion is poised to become a significant player in the precision oncology space, making it another company worth watching closely. Optimistic Outlook for Precision Oncology The precision oncology space is experiencing a golden era of innovation, with companies like Summit Therapeutics, Nuvectis Pharma, Silexion Therapeutics, and Scorpion Therapeutics leading the charge. As the focus shifts towards targeted therapies that address resistance mechanisms, the market is increasingly favoring companies with novel approaches and broad applications. Summit’s meteoric rise has shown that there is tremendous potential for companies that can demonstrate efficacy in overcoming cancer resistance. While Summit has already captured much of the current attention, companies like Nuvectis, Silexion, and Scorpion, with their earlier-stage pipelines, offer exciting opportunities for the industry to keep a close eye on. As these companies continue to report clinical data and advance through trials, the potential for breakthroughs in treating some of the most difficult cancers grows stronger. With targeted therapies offering the possibility of overcoming resistance without the need for chemotherapy, the future of cancer treatment looks brighter than ever. For those in the oncology space, keeping a close eye on emerging players like Nuvectis, Silexion, and Scorpion could lead to transformative developments as the field of precision oncology continues to evolve. * * * This update may include speculative forward looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those in the forward-looking statements as a result of various factors. the BioTech and Pharma industries are volatile and risky and readers are advised to seek out preffesional advice in the relevent feilds from licensed profesionals. This update is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. [ https://justpaste.it/ch2qt/pdf ]. Global Markets News Network is a commercial digital brand compensated to provide coverage of news and developments related to innovative companies as detailed in the full documentation and it is thus subject to conflicts of interest. Contact Details News Coverage ronald@futuremarketsresearch.com

September 19, 2024 07:45 AM Eastern Daylight Time

Transforming Textiles' Groundbreaking Fashion Line ‘Modality’ to Debut at Milan Fashion Week

Modality

Sweden / ThriveNewsWire / September 16, 2024 / Transforming Textiles AB fashion brand Modality, under the creative direction of Sara Rosberg, is set to make a significant impact on the runways of Milan Fashion Week. The groundbreaking collection themed 'Endangered Animals’ and named “ Fading Fables ” combines innovative Sense-Tex fabric technology, focusing on environmental conservation and sustainable fashion. The collection will be unveiled on September 20th, at Museo Della Scienza in Milan, hosted by Friend of the Earth and the World Sustainability Organization. The runway show, titled “ Beyond the Claim, ” will showcase certified fashion brands and materials by Friend of the Earth, including Sense-tex. Sense-Tex is an innovative biobased 5-fiber yarn technology that combines style, functionality, and sustainability. The Sense-Tex technology, which can be described as a “canvas”, enables sensors (external or embedded) to be applied and integrated onto or inside the fabric to measure vitals. Sense-Tex as a fabric offers health-enhancing benefits and strong ethical values, standing on its own as a sustainable textile without requiring technological integration. Due to pressing upcoming EU regulations affecting the industry, the organizers removed all added sensor tech for this show to focus on the Artistry and Sense-Tex as sustainable fabric. The sensor customization incurs higher costs per unit and requires research and development for each specific sensor project. Therefore, the company is seeking tech partnerships and collaborations with companies that are interested in tailoring their product with sensors to fit their specific needs and budgets. Sense-Tex is a certified material by Friend of the Earth that aligns with the upcoming new EU regulations for the Textile Industry, which requires 10% biobased material in all collections. The multifunctional Sense-Tex yarn and fabric developed by Transforming Textiles ( www.Sense-tex.com ) has also received a “Seal of Excellence ” from the Materials Connexion lab in NYC, where it became part of their exclusive materials library (addressing both the public and private sectors globally). The Sense-Tex yarn/fabric serves various verticals by scaling up the company (Transforming Textiles AB) with subsidiary divisions and a holding structure for the approved IP, as they aim to raise capital to scale up. The Transforming Textiles pitch deck can be reviewed here. This Fading Fables collection by Modality showcases the material's versatility and demonstrates how it can be used in various fashion styles, moods, and genres. Modality is presenting handmade pieces made by Sara Rosberg herself, using scrap fabrics and upcycled garments, combined with prints on Sense-Tex, seamlessly merging art, fashion, and sustainable textile solutions. “The Fading Fables collection is more than just a fashion collection,” says Sara Rosberg. “It tells a story, raises awareness, and highlights the inseparable connection between the future of fashion and the future of our planet. By utilizing upcycled materials and incorporating biobased technologies like Sense-Tex, we not only meet the new EU regulations but also set a new standard for the industry, helping them to transition into the new regulatory landscape.” The theme of the show centres on displacement and the plight of endangered animals, poignantly speaking to the loss of home and the need to flee. As models walk the runway, a powerful video will play in the background, depicting the destruction of animal habitats, the urgent need for conservation, and why we need to support Friend of the Earth and the World Sustainability Organisation. The video was created by Ayesha Saboor, Sara Rosberg, and Charlotte Kehler. The collection will also feature endangered animal-inspired accessories by Charlotte Kehler, made from waste and scrap fabric, with designed artwork printed on Sense-Tex fabric. Modality has partnered with Elobina.com and the Head of Operations, Vilma Gustafsson as a sustainable solution for designers. This collaboration allows Modality to create its own designs and utilize print-on-demand services. By focusing on smaller quantities and producing only what is necessary, this approach fosters a more sustainable production model. Sara Rosberg emphasizes, “ Sustainability is not just a trend, it is a necessity. This collection is more than just fashion; it is a call to action, urging the industry and consumers to embrace a more responsible relationship with our environment." For Buyers We offer the fashion garments showcased on the runway for pre-order sales to boutiques, retailers, and others through our look-book and website www.Modality.store. Please note that due to the complexity of producing Sense-Tex, the estimated delivery time is 5-6 months, but can vary. As some garments have been upcycled by hand, there may be small variations in the sourcing of identical fabrics for larger orders. We want to ensure that the buyers and retailers are aware of this extended timeline, as it differs from traditional textile materials and standard production. We have planned to coordinate bringing smaller orders together with the larger volume orders in one production batch in the coming weeks after MFW. Should we be unable to deliver the combined small quantities due to not reaching the MOQ of 1000kg, Modality will notify you beforehand. Sense-Tex is produced in 3 different factories to ensure the highest quality and performance for safety. A Yarn factory (Kipas), a fabric manufacturer (Ozen Mensucat), and a garment producer (Fethi Tekstil). Due to the brand being in a start-up phase without external funding, there are no fibers in stock, which will delay the production process in this first batch. In the future, when Modality has secured funding, lead times of Sense-Tex will be a maximum of 3 months, when Modality branches out with external funding as a subsidiary of Transforming Textiles AB. Modality also offers options to purchase only the yarn or the fabric in the desired quality, with Minimum Order Quantity (MOQ) requirements (1000kg= 40-60 rolls of fabric approx.) for volume production. These prices include Modality receiving a percentage of the future data revenue if sensors are applied and sold together with Sense-Tex. If there is a preference to order Sense-Tex without this clause when using sensors/tech, we add 20% on top of the current prices stated. However, there are ethical requirements attached from Modality and Transforming Textiles AB in the purchase order agreement to protect the end-user and ensure the handling of data is GDPR compliant and ethical use of the product. If you only wish to buy the fabric and not attach sensors/tech, the prices are as below. For independent designers, we aim to trade Sense-Tex through fabric retailers shortly, enabling purchases of small quantities for slow fashion production. Sense-Tex fabrics and yarns are available in three different compositions: Qty A, Qty B, and Qty C. Each composition caters to different production and manufacturing needs in the Fashion industry, accommodating different focuses and margins. Fabric Prices (Approximately) QTY A: 32EUR/M QTY B: 24 EUR/M QTY C: 21 EUR/M Yarn Prices (Approximately) QTY A: 78EUR/KG QTY B: 57EUR/KG QTY C: 47/EUR/KG **Minimum Order Quantity (MOQ) requirements 1000kg. Contact: We are open to discussing: Partnerships: Licensing: Custom-made designs: Co-Designing: Celebrity projects; Tailored versions of the collection; and any other projects in the creative sector where Sense-Tex could be used combined with storytelling. The Look-Book from the Fading Fables collection can be downloaded on www.Modality.store after the show on the 20th of September. Please email us for these inquiries to: info@modality.store For Tech Partnerships or other vertical projects or collaborations that might be mentioned in the pitch deck, please email: Info@transformingtextiles.com The pitch deck can be reviewed here. For more info on all companies in the Fading Fables project, please visit: www.Modality.store www.Sense-tex.com www. elobina.com www.Ckhelerdesign.se www.Maanaq.com www.friendoftheearth.org www.wso.org Press: Modality and Sara Rosberg will only accept scheduled written interviews at the moment. To request a written interview, please email: Info@transformingtextiles.com Contact Details Modality Sara Rosberg info@modality.store Company Website https://modality.store/

September 16, 2024 11:48 AM Eastern Daylight Time

Join Benchmark International's Exclusive Webinar "Seller Motivation: What Goes Into the Decision to Sell?"

Benchmark International

Are you considering selling your business? Deciding when and why to sell is one of the most significant decisions you’ll ever make as a business owner. While maximizing financial proceeds is often at the forefront of these decisions, it’s essential to recognize that it’s not the only factor. Life circumstances, time with family, and other qualitative considerations can often outweigh financial gain. To help you navigate this complex process, we invite you to join our upcoming webinar: Seller Motivation: What Goes Into The Decision To Sell? Space is filling up fast, so register today! Why You Should Register Selling a business is about more than just crunching the numbers. In this exclusive webinar, you’ll gain valuable insights into the full spectrum of motivations that drive business owners to sell. Understanding these motivations can help you make a well-rounded and informed decision about your business’s future. This webinar is a must-attend for business owners contemplating the sale of their business, particularly in today’s strong but disciplined market. By attending, you’ll be better equipped to evaluate both the financial and personal factors that play a crucial role in this life-changing decision. Whether you’re focused on securing a comfortable financial future or prioritizing time with loved ones, the information presented will help you weigh these considerations effectively. Spots are limited, so don’t miss this opportunity to secure your spot. What You’ll Learn This webinar offers actionable insights into the decision-making process for business owners. Here’s what you can expect to learn: The wide range of reasons why business owners choose to sell, beyond just financial incentives How personal life events, such as family needs and future aspirations, can influence your decision A look at the current M&A market and how buyers are approaching valuations How to balance personal and financial goals using the concept of indifference curves, which help weigh non-monetary values like time with family against financial returns By attending, you’ll gain the tools to make a decision that aligns with your long-term vision—both personally and financially. Spots Are Filling Fast – Register Now! If you’re ready to gain clarity on your motivations for selling and align your decision with both your personal and financial goals, this is the webinar for you. Don’t miss out—register now and take the first step toward making a well-informed, strategic decision about the future of your business. ABOUT BENCHMARK INTERNATIONAL: Benchmark International is a global M&A firm that provides business owners with creative, value-maximizing solutions for growing and exiting their businesses. Benchmark International has handled over $11 billion in transaction value across various industries from offices across the world. With decades of M&A experience, Benchmark International’s transaction teams have assisted business owners with achieving their objectives and ensuring the continued growth of their businesses. The firm has also been named the Investment Banking Firm of the Year by The M&A Advisor and the Global M&A Network as well as the #1 Sell-side Exclusive Privately-held M&A Advisor in the World by Pitchbook and Refinitiv's Global League Tables. Contact Details Brittney Zoeller +1 813-898-2350 zoeller@benchmarkintl.com Company Website https://www.benchmarkintl.com/

September 16, 2024 09:54 AM Eastern Daylight Time

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Flash Transforms Parking at Denver International Airport

Flash

Flash, the leading end-to-end parking technology platform, announced today it has completed an overhaul of public and employee parking at Denver International Airport (DEN) through a contract the City and County of Denver awarded in August 2024. In just 22 days, Flash deployed its platform across the airport’s nine public and employee parking garages and lots, bringing a state-of-the-art parking experience to DEN’s 40,000 employees and the 77.8 million passengers they serve annually. "Flash’s commitment to DEN has been tremendous and we look forward to a bright future that provides innovative solutions to improve the customer experience," said Mark Nagel, Senior Vice President of Parking and Commercial Transportation, Denver International Airport. In its first few weeks of deployment, DEN reports improved traffic flow and reduced wait times for vehicles entering and exiting the airport’s parking facilities. DEN’s deployment of Flash’s platform spans 144 lanes and features 137 kiosks, 97 license plate recognition (LPR) lanes, and 49 automatic vehicle identification (AVI) lanes. With the new AVI lanes, employees can enter and exit automatically in seconds via vehicle-mounted passes that require no interaction with their phones or kiosks. “DEN is the sixth busiest airport in the world and sees millions of parking transactions each year, requiring the highest service level,” said Flash CEO Dan Sharplin. “Our technology breadth and industry-leading scale, plus our maniacal focus on the driver experience, made us confident we could support DEN’s traffic volumes and service levels while getting passengers and employees through parking transactions quickly, and it’s hugely gratifying to see it live.” DEN also benefits from the Flash platform’s design as an enhanced cloud-based parking solution. In the event of an internet, payment processor, network or cloud disruption, the platform maintains continuous operations and critical payment processing capabilities so the airport’s parking facilities stay up and running. About Flash Flash is a pioneering technology company bringing seamless parking and EV charging experiences to drivers through a first-of-its-kind digital ecosystem. Flash’s platform connects reservable parking and charging in the apps drivers use every day with garage, surface lot, event, and valet parking locations—connected and controlled via a cloud-based operating system with unrivaled intelligence. Customer-obsessed brands partner with Flash to deliver digital, easy-to-use, reliable, and increasingly frictionless experiences to drivers eager to pay for a solution that eliminates wasted time, excess emissions, and stress. The solution has arrived.. Visit www.flashparking.com to learn more. Contact Details Ray Young +1 512-694-6097 ray@razorsharppr.com Company Website https://www.flashparking.com/

September 12, 2024 09:00 AM Central Daylight Time

MANDUKA® Launches the Dhara Yoga Apparel Collection for Women

Manduka

Manduka, creators of high performance yoga gear and the #1 choice of yoga teachers worldwide, revealed today its Dhara collection, a five-piece line of foundational yoga apparel designed for comfort, movement, and sustainability. Honoring a request from the yoga community to provide apparel they can feel good about wearing and how it is made, the Dhara collection was created with the highest standards in performance and sustainability. It’s the newest drop in the company’s plan to set the benchmark for environmentally conscious leadership in the performance wellness industry through 2025. The Dhara Collection offers a simple and easy to wear combination of premium quality, sustainability, and performance in yoga apparel. It’s designed with 88% recycled materials, a difference you can actually feel when wearing. The collection is also free from many of the harmful chemicals that can be found in other performance wear like pesticides, BPA, PFAS and formaldehyde. Technical, breathable and buttery soft, it addresses the demand for thoughtfully designed activewear that doesn’t compromise on style or functionality. “Manduka is on a path to elevate the performance and sustainability of its hardgoods and apparel lines over the next several years,” said Pamela Levine, CEO Manduka. “You will see Manduka build on its legacy of creating soulfully engineered products through usage of renewed materials, innovative manufacturing methods, and pre and post consumer waste reduction efforts. We are excited to unveil the Dhara collection as the first in this roadmap to further seamlessly integrate Manduka’s high-performance standards with a deep commitment to sustainability at a level not yet seen in the industry.” The translation of Dhara means earth with an homage to create a product with attention to the recycled materials that make up this collection. The timeless pieces are designed to offer a second skin feel that enhances your practice and doesn’t distract. The Dhara collection is made up of five ultra-soft pieces including: Dhara Bra - sleek, supportive pullover bra with four-way stretch. Features a flattering scoop neckline, low open back, and hidden underbust band. Dhara Capri Legging - high waisted fit and sleek styling makes it a versatile cropped legging with long lasting comfort. Dhara Tank - sophisticated racer back tank with a modest cropped fit. Designed with a double-knit construction with four-way stretch allows you to flow effortlessly. Dhara Legging - high waisted fit and sleek styling makes it a versatile legging with long lasting comfort. Created with a matte finish fabrication and four-way stretch ensure you move effortlessly and feel at one with your body. The Dhara collection is available in a range of colors like Avian Heather, Clay Heather, Midnight Heather, Phantom and Lions Mane and has an MSRP of $58-$90. The line will be available through www.manduka.com yoga studios and select national retailers. About Manduka Manduka was founded in 1997 with the simple idea that a better yoga mat could make a world of difference. For generations, Manduka has revolutionized the yoga space by providing purposefully crafted products that enable a more joyful practice, whatever that looks like for you. The brand's name pays homage to the Mandukasana, a challenging, thought-provoking, and freeing pose that inspires joy, laughter, and simplicity. Their loyal community of teachers, yogis and enthusiasts have been cultivated by the quality, intentionality, durability, and performance of their Mats and yoga accessories. Their unparalleled craftsmanship and sustainability efforts remain celebrated widely in wellness communities throughout the world. From their teacher-recommended PRO Series Mat to their Free Online Yoga Classes, Manduka is on a mission to inspire daily practice in all its modern forms for those seeking connection to self and humbly works in service of the community. Practice On. Website | Instagram | TikTok | YouTube Contact Details Harmonica Amber Cardullo amber@harmonica.co Company Website https://www.manduka.com

September 12, 2024 09:01 AM Eastern Daylight Time

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ASSOCIATION OF PICKLEBALL PLAYERS TO DOUBLE EVENT CALENDAR IN 2025

AOPP

The APP increases its commitment to growing the sport of pickleball with more opportunities for pro and amateur players, stronger investment in player development initiatives and more national television exposure for APP Tour events The Association of Pickleball Players (APP) has announced a dramatic expansion of its 2025 tournament calendar featuring nearly 50 world-class competitions throughout the year. Beginning in January 2025, the APP’s seventh year will showcase its most robust calendar ever and celebrates its first year at its state-of-the-art headquarters at The Fort in Fort Lauderdale, Fla. “The APP has enjoyed a strong 2024, positioning us perfectly for even more significant growth in 2025,” commented APP Founder Ken Herrmann. “The experiences the APP provides for pickleball players, across all ages and all abilities, sets the standard in pickleball worldwide. We remain committed to delivering the absolute best experience for all players and paving the way for America’s future pickleball stars. As we continue to grow, we are leading the world in the sport’s development.” Expanded Opportunities for Pros and Amateurs The APP Tour is meeting the increased demand for opportunities to play across all ages and skill levels by doubling competitions in 2025, highlighted by: 14 nationally televised APP Tour events – with increased prize purses – will include four APP Tour Majors, eight USA Pickleball “Golden Ticket” tournaments, the APP Women’s Open presented by The James and the APP U.S. Collegiate Championships More than 20 new APP Tour competitions serving tens of thousands of pickleball players at the pro and amateur level across the United States, including the return of the AARP Champions Cup and the APP Atlantic Cup More Nationally Televised Events The APP Tour also is expanding its industry-leading linear broadcast schedule to more than 55 hours in 2025. This includes 14 nationally televised APP Tour events, giving the nation’s top pickleball pros unprecedented visibility on a national stage. Pickleball fans across the country will enjoy unparalleled access to the sport’s most competitive matches, allowing them to experience the excitement firsthand. “We’re thrilled to provide more fans with access to pickleball’s biggest moments, helping elevate the sport to new heights,” said APP Chief Marketing Officer Tom Webb. “Expanding our linear TV coverage in 2025 is not only a testament to pickleball’s growing national appeal but also crucial in giving our pro players the platform they deserve while driving the sport’s continued growth across the country.” Player Development Initiatives The APP's commitment to player development and growing the game among youth pickleball players is unmatched, as demonstrated by an expanded APP Next Gen schedule in 2025. Aspiring pickleball professionals aged 23 and younger will have the opportunity to participate in four APP Next Gen Series events and four APP Next Gen II events, competing for prize money while receiving mentorship from top APP Tour professionals. This is accompanied by the APP Academy’s January launch at The Fort, the APP’s global headquarters in Fort Lauderdale, FL. This marks the world’s first pickleball academy, offering pickleball training and development rooted in the same spirit as development academies in the racquet sports world. The APP Academy will provide a platform for aspiring APP Next Gen, APP Collegiate and junior pickleball players ages 12-18. Further details will be announced this Fall. International Events The global expansion of competitive and recreational pickleball remains a priority for the APP, which is proud of its status as the primary steward of the sport’s rapid international growth. The APP’s 2025 initiatives will support several international events, with the full slate to be announced later. Stay Connected with the APP The pickleball community can stay in the know on the latest APP updates by following the APP’s Instagram, X, Threads, TikTok, Facebook and LinkedIn channels. The complete 2025 APP event schedule—including dates, locations, venues and broadcast information—will be announced in the coming weeks on theapp.global. The Association of Pickleball Players (APP) provides opportunities for pickleball players of all ages and skill levels - professionals, amateurs and recreational - to compete in world-class pickleball events for the opportunity to win prize money and be seen on more than 40 hours of nationally televised pickleball action on CBS Sports, ESPN and FOX Sports. Since its launch in 2019, the APP has operated the first and only pro and amateur pickleball tour fully and officially sanctioned by USA Pickleball and became the first pickleball organization ever to establish an official headquarters and training center with The Fort in Fort Lauderdale, Fla. The APP Tourâs 2024 schedule features the most robust pickleball showcase across pro and amateur competitions, with 20 events across the country offering various combinations of single, doubles and mixed doubles play as well as pro team competitions. The APP prides itself on growing the game and developing the next generation of pickleball champions through its nationwide network of APP UTR Sports Pickleball Leagues, and the Doubles Dink for Cancer fundraising program benefitting the American Cancer Society; support of international pickleball events and the APPâs Atlantic Cup, featuring Team USA vs. Team Europe; and youth initiatives including the APP Junior Circuit, APP Next Gen Series and APP Next Gen U.S. National Team. The 2024 tournament schedule, recent news and additional information about the APP are available at theapp.global and on Instagram, X, Threads, TikTok, Facebook and LinkedIn. APP Media Contact: Daniel Sagerman at dsagerman@theapp.global or (847) 800 8182 Contact Details Daniel Sagerman +1 847-800-8182 dsagerman@theapp.global Company Website https://theapp.global

September 12, 2024 08:00 AM Central Daylight Time

Leading Beauty Retailer Credo Beauty Debuts Private Label Skincare Line: Credo Skincare

Credo Beauty

Credo, the specialty clean beauty retail pioneer, is proud to announce the launch of its own eponymous skincare line, Credo Skincare. The specialty retailer has raised the bar introducing a benefit-driven collection of skincare products focused on the #1 skin concern gathered from clients – hydration – while continuing to challenge and elevate standards for clean and sustainable products and packaging. A cohesive easy to navigate cleanser and moisturizer system meets wanted gold standards. A decade ago, Credo disrupted an underregulated industry as a catalyst for positive change spurring a tidal wave of conscientious product and packaging innovation. Now after accruing 10 years of customer feedback, experience, and data Credo Skincare was developed according to what they found matters most. Ultimately hydration was the stand-out concern for clients. And through in-depth analysis, Credo determined the top ingredient and search terms according to what customers want from their products to deliver that and more. Through their access to the best in business partners, they created results-driven formulas packed with clinically proven actives and sustainably- minded packaging - every aspect of Credo Skincare is transparent and powerfully effective. Credo Skincare’s first collection is comprised of two cleansers ($44 each) and four moisturizers ($64 each) that service skin conditions surrounding primary concerns - dry skin, sensitivity and redness, dullness, and aging - by nourishing the skin and protecting its microbiome through today’s most powerful active combinations. Their formulations are based on key ingredient search terms and skincare concerns. As well, each product contains the transformative power of upcycled vetiver root extract, ethically harvested by a local cooperative in Haiti. Vetiver root is an antioxidant-loaded, potent wonder grass that supports the protection of the skin’s barrier for a vibrant skin tone and a nourished complexion while improving skin texture and reducing the appearance of pores and wrinkles. Credo Skincare’s goals are to provide an easy two step, effective regimen for healthy, hydrated skin that makes customers look and feel their best. Clinicals have proven 27% improvement in hydration after 24 hours, 31% improvement in hydration instantly, and an improvement in the skin barrier function instantly and after 24 hours. ● Deep Thirst Hydrating Cleanser ($44): A transformative formula to deeply cleanse while retaining moisture. ● True Timeout Calming Cleanser ($44): Designed to soothe and calm sensitive skin. ● Deep Thirst Hydrating Moisturizer ($64): Provides intense hydration with lasting effects. ● True Timeout Calming Moisturizer ($64): Helps alleviate sensitivity and redness. ● Radiance Rising Brightening Moisturizer ($64): Brightens dull skin and enhances radiance. ● Rewinder Anti-Aging Moisturizer ($64): Reduces the appearance of wrinkles and fine lines. Beyond that as a retailer, Credo Beauty continues to drive the packaging and social standards that are the hallmarks of tomorrow. Every pump and cap in the Credo Skincare collection is comprised of a first-of-its kind PCR resin, including beauty waste packaging collected in Credo Beauty stores nationwide through Pact Collective, the non-profit Credo Beauty co-founded to divert beauty packaging from landfills. ● The Credo pump was created with Pact’s NewMatter material, a mixture of hard-to-recycle material or landfill and ocean-bound plastic. ● The first run of NewMatter pumps eliminated the need for 500 kg of virgin plastic (500 kg of recycled plastic used is equivalent to 11 cubic meters of landfill space or ~2,900 gallons of space!) ● Every 38 pumps eliminate one pound of material going to the landfill or ocean. “The benefit of listening to 10 years of customers' desires and skin concerns compelled us to create this line. Years of data drove the ingredient compositions of these products so that we could exceed our customers’ expectations for efficacy. Our Credo Clean Standard is already rigorous and difficult to attain but we wanted to challenge ourselves with how our own brand could take clean innovation to new heights from full disclosure of fragrance ingredients and packaging innovation to exceeding the minimum requirements to check certain boxes, Credo Skincare raises the bar on what is possible and what can become the future baseline,” says Co-Founder and CEO Annie Jackson. Availability: Credo Skincare will be available for purchase starting September 12, 2024, at all Credo brick and mortar store locations and on www.credobeauty.com. Media Contact: press@credobeauty.com About Credo Beauty: Credo Beauty offers today’s largest clean and sustainably minded beauty assortment in North America, across color, skincare, haircare and fragrance, partnering with over 120 leading brands, such as Westman Atelier, ILIA, OSEA, True Botanicals and LolaVie. Having built the strictest and lengthy guidelines, “The Credo Clean Standard™”, customers can trust that they are purchasing the most effective, innovative products with safer ingredients with an emphasis on sustainable, natural and ethical materials. Trained makeup artists and estheticians (who are continually being educated by Credo Beauty and our brands) offer an exceptional experience both in-store and online. Visit one of the 15 brick-and-mortar store locations or www.credobeauty.com. Credo Beauty is backed by Next World Evergreen, a San Francisco-based private equity firm that invests in conscious consumer brands across sectors like clean beauty, personal care, health and wellness, sustainable lifestyle, and better-for-you food and beverage. Visit https://www.nextworldevergreen.com/ About Pact Collective: With an industry that generates over 120 billion packages every year, most ending up in landfill – they’re often too small, too flexible, or made of too many materials to be traditionally recycled. All those tiny cosmetic contraptions? They’re headed for the trash. Pact is a nonprofit collective uniting the beauty industry to take responsibility for our packaging waste and work collaboratively toward circular packaging solutions. Visit https://www.pactcollective.org/ Contact Details Amanda Smeal +1 844-692-7336 press@credobeauty.com

September 12, 2024 08:04 AM Eastern Daylight Time

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THE WORLD'S PREMIER IMMERSIVE GAMING EXPERIENCE TO UNVEIL ITS FIRST LOCATION IN COLUMBUS THIS SEPTEMBER

Activate

Activate, the trailblazing live-action gaming sensation taking TikTok by storm, will unveil its newest location in Columbus on September 14, 2024, following the success of its first Ohio location in Cincinnati. Guests are invited to dive into the world of immersive gameplay that has captured the hearts of gamers worldwide! This extraordinary venue is set to elevate the entertainment scene to new heights at its vibrant new location: 8735 Lyra Drive, Columbus, OH 43240. From September 14 to 15, Activate is set to launch its grand opening weekend with free admission and extraordinary surprises. Guests can register here. This spectacular new venue will invite an even larger audience to dive into the exhilarating fusion of physical challenges and digital gaming that has made Activate a sensation. Prepare for an unforgettable experience as Activate brings its renowned thrill to a whole new level! Activate is redefining the future of gaming, unleashing its groundbreaking live-action experiences across the U.S. with an unstoppable wave of expansion. With 40 thriving locations worldwide and a staggering 2.5 million players, Activate combines state-of-the-art technology with heart-pounding challenges, creating an adrenaline-fueled social adventure like no other. This isn't just gaming; it's an electrifying global phenomenon that’s captivating players worldwide. "We're beyond excited to bring Activate to Columbus and share our passion for cutting-edge, interactive adventures," says Will Gray, Director of Marketing at Activate. "This new location will offer our signature mix of physical excitement and digital fun to even more people. We can't wait to light up this vibrant community with the thrill of our unique gaming experience and welcome a whole new group of adventurers." Activate Columbus's cutting-edge gaming facility invites players of all ages and skill levels to explore and create their unique gaming experiences. Here’s what to expect: Top gaming rooms include the TikTok viral sensation Mega Grid with 500+ multi-activated rainbow-colored tiles, blasting the beaming bullseye in a game called Strike, and feel like a modern-day spy in the Laser room. Guests can sign up in groups of two to five players. Through progress tracking via Activate’s high-tech electronic RFID wristbands, players can rack up points, leveling up and earning prizes along the way. Try Level 1 easy or take it to Level 10 extreme. Play as a team in cooperative mode, or challenge your friends in competitive mode games. Additional Activate locations are set to open in 2024 across the U.S. in markets such as Detroit, Bloomington and Austin. Today, Activate operates over 40 locations across Canada and the U.S. PLAN YOUR VISIT Wear activewear and flat, closed-toe shoes. Where: 8735 Lyra Drive Columbus, OH 43240. When: Monday through Thursday, 12 p.m to 9 p.m. | Friday, 10 a.m to 11 p.m | Saturday, 9 a.m. to 11 p.m. | Sunday, 9 a.m. to 10 p.m. Cost: Starting at $19.99 per player Mon-Thurs and $24.99 per player Fri-Sun (and Holidays). For a sneak peek into Activate’s action-packed gaming experience, click here. Click here for high-res assets Activate is the world’s first active gaming experience where players #EnterTheGame. Activate offers a unique blend of physical activity and gaming that promotes a healthy lifestyle. Each Activate location provides fun and interactive rooms for players to compete, earn stars and track achievements. With the global headquarters located in Winnipeg, Canada, Activate has grown to 30 locations across Canada, the U.S. and now the world! To join the active gaming movement, visit playactivate.com. Follow Activate on social media: Facebook: Activate Instagram: @activategames TikTok: @activategames Contact Details Jive PR + Digital Jalila Singerff +1 613-614-6777 jalila@jiveprdigital.com Company Website https://playactivate.com

September 12, 2024 08:00 AM Eastern Daylight Time

Connecting Brands With The Massive Gaming Community

Benzinga

By Johnny Rice, Benzinga Justin Kenna, CEO of GameSquare Holdings Inc (NASDAQ: GAME) was recently a guest on Benzinga’s All-Access. GameSquare is a next generation media company with a goal of revolutionizing the way brands and game publishers connect with hard-to-reach Gen Z, Gen Alpha, and millennial audiences. Its media, entertainment and technology capabilities aim to drive compelling outcomes for creators and to maximize its brand partners’ return on investment. The company’s purpose-built platform provides award-winning marketing and creative services, offers data and analytics solutions, and amplifies awareness through FaZe Clan, a professional esports and entertainment organization. Watch the full interview here: Featured photo by Sean Do on Unsplash Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 10, 2024 08:45 AM Eastern Daylight Time

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